1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE

1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE - Names and Identifiers

Name	1-(2-chloro-6-fluorobenzyl)piperazine
Synonyms	AKOS B020144 BUTTPARK 338-78 ART-CHEM-BB B020144 1-(2-chloro-6-fluorobenzyl)piperazine 1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE 1-(2-CHLORO-6-FLUOROBENZYL) PIPERAZINE HCL 1-[(2-bromo-6-fluorophenyl)methyl]piperazine
CAS	215655-20-2
InChI	InChI=1/C11H14ClFN2/c12-10-2-1-3-11(13)9(10)8-15-6-4-14-5-7-15/h1-3,14H,4-8H2

1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE - Physico-chemical Properties

Molecular Formula	C11H14ClFN2
Molar Mass	228.69
Density	1.202 g/mL at 25 °C (lit.)
Boling Point	145 °C
Flash Point	>230°F
Vapor Presure	0.00118mmHg at 25°C
pKa	9.01±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	n20/D 1.5470(lit.)
MDL	MFCD00816605

1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust.
WGK Germany	3
HS Code	29339900
Hazard Note	Corrosive

1-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINE - Introduction

1-(2-chroo-6-fluorobenzyl) piperazine is an organic compound with the chemical formula C11H14ClFN2. It is a solid powder with a white or white-like crystalline appearance.

1-(2-choro-6-fluorobenzyl) piperazine is commonly used as a pharmaceutical intermediate. It is an important pharmaceutical compound commonly used in the synthesis of drugs such as antipsychotics and antidepressants.

The method for preparing 1-(2-chloro-6-fluorobenzyl)piperazine can be obtained by chlorinating 2-chloro-6-fluorobenzyl to 2-chloro-6-fluorobenzyl chloride, it is then obtained by reaction with piperazine.

Regarding the safety information of this compound, the following points need to be noted:
1. 1-(2-chloro-6-fluorobenzyl)piperazine may be irritating to the eyes, skin and respiratory tract, so it is necessary to take appropriate protective measures when handling, such as wearing chemical protective glasses, protective clothing and gloves.
2. Avoid inhalation of the compound dust or gas, such as the need to operate should be good ventilation.
3. The compound should be kept away from the fire and oxidant, stored in a dry, cool, ventilated place.
4. When using the compound, the relevant safety operation procedures and safety operation guidelines should be observed.

Please note that this is just a general overview. In practical applications, more detailed evaluation and operation are required according to specific conditions.

Last Update：2024-04-09 20:49:11