1-(2-CHLOROETHYL)-4-FLUOROBENZENE

1-(2-CHLOROETHYL)-4-FLUOROBENZENE - Names and Identifiers

Name	1-(2-chloroethyl)-4-fluorobenzene
Synonyms	4-FLUOROPHENETYL CHLORIDE 4-FLUOROPHENETHYL CHLORIDE 2-(4-FLUOROPHENYL)ETHYL CHLORIDE 1-(2-CHLOROETHYL)-4-FLUOROBENZENE 1-(2-chloroethyl)-4-fluorobenzene 1-CHLORO-2-(4-FLUOROPHENYL)ETHANE 2-(4-FLUOROPHENYL)ETHYL CHLORIDE EP 4-Fluorophenethyl chloride~2-(4-Fluorophenyl)ethyl chloride
CAS	332-43-4
EINECS	206-364-9
InChI	InChI=1/C8H8ClF/c9-6-5-7-1-3-8(10)4-2-7/h1-4H,5-6H2

1-(2-CHLOROETHYL)-4-FLUOROBENZENE - Physico-chemical Properties

Molecular Formula	C8H8ClF
Molar Mass	158.6
Density	1,507 g/cm3
Boling Point	89 °C
Flash Point	98-99°C/26mm
Solubility	Benzene, Methanol (Slightly)
Vapor Presure	0.373mmHg at 25°C
Appearance	Oil
Color	Colourless
BRN	2079481
Storage Condition	Refrigerator
Refractive Index	1.507
MDL	MFCD00155000

1-(2-CHLOROETHYL)-4-FLUOROBENZENE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/38 - Irritating to eyes and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	1760
Hazard Note	Irritant

1-(2-CHLOROETHYL)-4-FLUOROBENZENE - Introduction

1-(2-chloroethyl)-4-fluorobenzene is an organic compound with the chemical formula C8H7ClF. The structure has a fluorine atom and a chloroethyl group attached to the benzene ring.

Nature:
1-(2-chloroethyl)-4-fluorobenzene is a colorless liquid with a special smell at room temperature. It is soluble in organic solvents such as ethanol, ethers and chlorinated hydrocarbons, but slightly soluble in water.

Use:
1-(2-chloroethyl)-4-fluorobenzene is commonly used as a chemical reagent in organic synthesis. It can be used in the preparation of drugs, such as non-steroidal anti-inflammatory drugs and pesticides. In addition, it can also be used to prepare intermediates and functional compounds in organic synthesis.

Method:
1-(2-chloroethyl)-4-fluorobenzene can be prepared by alkylation of benzene and vinyl chloride in the presence of hydrofluoric acid. The specific steps are to add benzene and vinyl chloride into the reactor, add an appropriate amount of hydrofluoric acid as a catalyst, and react for a period of time at an appropriate temperature and pressure, and finally obtain the target product through extraction and purification.

Safety Information:
1-(2-chloroethyl)-4-fluorobenzene is an organic compound that is irritating. In the use of the process should pay attention to protective measures, such as wearing appropriate protective glasses, gloves and protective clothing. Avoid inhaling its vapors and avoid contact with skin and eyes. The relevant safety data sheets and operating procedures should be read and followed before operation.

Last Update：2024-04-09 20:52:54