1-(2-Chloro-5-nitrophenyl)ethan-1-one
1-(2-Chloro-5-nitrophenyl)ethan-1-one
CAS: 23082-50-0
Molecular Formula: C8H6ClNO3
1-(2-Chloro-5-nitrophenyl)ethan-1-one - Names and Identifiers
| Name | 1-(2-Chloro-5-nitrophenyl)ethan-1-one |
| Synonyms | 2-CHLORO-5-NITROACETOPHENONE 2'-CHLORO-5'-NITROACETOPHENONE 1-(2-chloro-5-nitrophenyl)ethanone 1-(2-CHLORO-5-NITRO-PHENYL)-ETHANONE 1-(2-Chloro-5-nitrophenyl)ethan-1-one 1-(2-chloro-5-nitrophenyl)ethan-1-one Ethanone, 1-(2-chloro-5-nitrophenyl)- |
| CAS | 23082-50-0 |
| EINECS | 245-421-2 |
| InChI | InChI=1/C8H6ClNO3/c1-5(11)7-4-6(10(12)13)2-3-8(7)9/h2-4H,1H3 |
1-(2-Chloro-5-nitrophenyl)ethan-1-one - Physico-chemical Properties
| Molecular Formula | C8H6ClNO3 |
| Molar Mass | 199.59 |
| Density | 1.378±0.06 g/cm3(Predicted) |
| Melting Point | 62 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 244.8±20.0 °C(Predicted) |
| Flash Point | 101.8°C |
| Vapor Presure | 0.0298mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.573 |
1-(2-Chloro-5-nitrophenyl)ethan-1-one - Introduction
1-(2-Chloro-5-nitrophenyl)ethan-1-one is an organic compound with the chemical formula C8H6ClNO3. It is a yellow solid with a special smell.
One of the main uses of 1-(2-Chloro-5-nitrophenyl)ethan-1-one is as an intermediate in organic synthesis. It can be used in the synthesis of various drugs, dyes and pesticides and other compounds. In addition, it can also be used for reduction, substitution and carboxyl activation reactions in organic synthesis.
1-(2-Chloro-5-nitrophenyl)ethan-1-one can be synthesized by reacting acetophenone with nitric acid and hydrochloric acid. The reaction first introduces a chlorine atom on acetophenone, and then introduces a nitro group on the benzene ring by nitration. The reaction conditions need to be precisely controlled to ensure yield and selectivity.
Regarding safety information, 1-(2-chloroo-5-nitrophenyl) ethan-1-one is a flammable substance and should be kept away from open flames and high temperatures. Personal protective equipment such as goggles, gloves and protective clothing must be worn when handling this compound. Avoid inhaling compound dust or contact with skin. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, this compound should be stored and handled properly to avoid contact with substances such as strong oxidants or strong acids.
One of the main uses of 1-(2-Chloro-5-nitrophenyl)ethan-1-one is as an intermediate in organic synthesis. It can be used in the synthesis of various drugs, dyes and pesticides and other compounds. In addition, it can also be used for reduction, substitution and carboxyl activation reactions in organic synthesis.
1-(2-Chloro-5-nitrophenyl)ethan-1-one can be synthesized by reacting acetophenone with nitric acid and hydrochloric acid. The reaction first introduces a chlorine atom on acetophenone, and then introduces a nitro group on the benzene ring by nitration. The reaction conditions need to be precisely controlled to ensure yield and selectivity.
Regarding safety information, 1-(2-chloroo-5-nitrophenyl) ethan-1-one is a flammable substance and should be kept away from open flames and high temperatures. Personal protective equipment such as goggles, gloves and protective clothing must be worn when handling this compound. Avoid inhaling compound dust or contact with skin. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, this compound should be stored and handled properly to avoid contact with substances such as strong oxidants or strong acids.
Last Update：2024-04-09 20:52:54
