1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil-d3 - Names and Identifiers
1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil-d3 - Physico-chemical Properties
Molecular Formula | C10H14N2O5
|
Molar Mass | 242.23 |
Melting Point | 184-184°C |
Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | -20°C Freezer |
Stability | Hygroscopic |
1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil-d3 - Introduction
Thymidine-d3 (Thymidine-d3) is a breast pyrimidine nucleoside containing a deuterium isotope. The following is a description of its nature, use, formulation and safety information:
Nature:
- Thymidine-d3 is a white crystalline solid, soluble in water and some organic solvents.
-Its molecular formula is C10H13D3N2O5, and its relative molecular mass is 245.27g/mol.
Use:
- Thymidine-d3 are primarily used as isotopic markers in scientific research.
-It is often used to track and study the process of DNA synthesis and metabolism.
- Thymidine-d3 can also be used as radioactive tracers and used in research fields related to nuclear medicine.
Method:
-The preparation of Thymidine-d3 is generally carried out by chemical synthesis methods.
-First, The deuterated mixture is reacted with a compound containing thoracic pyrimidine-2 '-aldehyde.
-After the reaction, the final Thymidine-d3 product is obtained through purification, crystallization and other steps.
Safety Information:
-The toxicity of Thymidine-d3 is relatively low, but it still needs to be handled with caution.
-When using or handling Thymidine-d3, personal protective equipment required by the laboratory, such as gloves and glasses, should be worn to prevent injury from contact with skin, eyes or inhalation.
-When storing, store the Thymidine-d3 in a dry environment, away from oxidants and fire sources.
-For further safety information and operating precautions, it is recommended to refer to the relevant safety data sheets and guidelines.
Last Update:2024-04-10 22:29:15