1-(2-Fluoro-5-nitrophenyl)ethanone
1-(2-Fluoro-5-nitrophenyl)ethanone
CAS: 79110-05-7
Molecular Formula: C8H6FNO3
1-(2-Fluoro-5-nitrophenyl)ethanone - Names and Identifiers
| Name | 1-(2-Fluoro-5-nitrophenyl)ethanone |
| Synonyms | 2'-Fluoro-5'-nitroacetophenone 1-(2-Fluoro-5-nitrophenyl)ethanone Ethanone,1-(2-fluoro-5-nitrophenyl)- 1-(2-Fluoro-5-Nitrophenyl)Ethan-1-One 1-(2-Fluoro-5-nitrophenyl)ethan-1-one ethanone, 1-(2-fluoro-5-nitrophenyl)- 1-(2-Fluoro-5-nitrophenyl)ethan-1-one, 3-Acetyl-4-fluoronitrobenzene |
| CAS | 79110-05-7 |
| EINECS | 639-356-2 |
| InChI | InChI=1/C8H6FNO3/c1-5(11)7-4-6(10(12)13)2-3-8(7)9/h2-4H,1H3 |
1-(2-Fluoro-5-nitrophenyl)ethanone - Physico-chemical Properties
| Molecular Formula | C8H6FNO3 |
| Molar Mass | 183.14 |
| Density | 1.336±0.06 g/cm3(Predicted) |
| Melting Point | 53-54 °C |
| Boling Point | 241.0±20.0 °C(Predicted) |
| Flash Point | 99.6°C |
| Vapor Presure | 0.0367mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.537 |
1-(2-Fluoro-5-nitrophenyl)ethanone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
1-(2-Fluoro-5-nitrophenyl)ethanone - Reference Information
| application | 1-(2-fluoro-5-nitrophenyl) ethyl-1-one is an organic intermediate, which can be prepared from 2 '-fluoroacetophenone through nitration reaction as raw material, and can be used as an organic synthesis intermediate and pharmaceutical intermediate, it is mainly used in laboratory research and development process and chemical production process. |
| preparation | add 2 '-fluorine-acetophenone (90.0g) dropwise to mechanically stirred slurry (93-98%, 360 mL) of concentrated H2SO4 at -42 ℃, 652 mmol) and fuming nitric acid (53.1 mL) in concentrated H2SO4(129 mL). The slurry was stirred at -42 ℃ for 30 min. Slowly pour the mixture on 1.3kg ice. Add water (1 L) to the mixture. The product precipitates from the solution. After all the ice melts, the product is filtered to collect. Dissolve the solids with EtOAc. The organic layer was washed with 5% Na2CO3 (2 x 300 mL), water (300 mL) and brine (300 mL) and dried with Na2SO4. It was filtered and the filtrate concentrated to obtain compound 1-(2-fluoro-5-nitrophenyl) ethyl-1-one (115g) as a solid. |
Last Update：2024-04-09 21:04:16
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Mobile: +86-18621343501
QQ: 2881950922
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Spot supply
Product Name: 1-(2-Fluoro-5-nitrophenyl)ethanone Visit Supplier Webpage Request for quotationCAS: 79110-05-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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View History
1-(2-Fluoro-5-nitrophenyl)ethanone
3,5-DIBROMO-2-METHYLTHIOPHENE
134720-04-0
2,2,6,6-Tetramethylpiperidone-4-toluenesulfonate
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17084-08-1
3,5-DIBROMO-2-METHYLTHIOPHENE
134720-04-0
2,2,6,6-Tetramethylpiperidone-4-toluenesulfonate
ISOAMYLBENZENE
2-氨基-2-(2,6-二氟苯基)乙酸盐酸盐
2-Amino-1-(4-chlorophenyl)ethanol
2-((Trimethylsilyl)Ethynyl)Aniline
(Methoxymethyl)trimethylsilane
17084-08-1