1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil
2'-Amino-D-uridine
CAS: 26889-39-4
Molecular Formula: C9H13N3O5
1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil - Names and Identifiers
| Name | 2'-Amino-D-uridine |
| Synonyms | 2'-NH2-dU 2'-NH2-2'-DU 2'-AMINO-D-URIDINE 2'-Amino-D-uridine Uridine, 2'-amino-2'-deoxy- 2'-Amino-2'-deoxy-D-uridine 1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil 2''-AMINO-2''-DEOXYURIDINE (2''-DEOXY-2''-AMINOURIDINE) 1-[3-AMINO-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PYRIMIDINE-2,4-DIONE |
| CAS | 26889-39-4 |
| InChI | InChI=1/C9H13N3O6/c10-9(17)6(15)4(3-13)18-7(9)12-2-1-5(14)11-8(12)16/h1-2,4,6-7,13,15,17H,3,10H2,(H,11,14,16)/t4-,6-,7-,9-/m1/s1 |
1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil - Physico-chemical Properties
| Molecular Formula | C9H13N3O5 |
| Molar Mass | 243.22 |
| Density | 1.555±0.06 g/cm3(Predicted) |
| Melting Point | 196-198 °C(Solv: ethanol (64-17-5)) |
| Water Solubility | Partly soluble in water. |
| Appearance | Powder |
| Color | Off-white to Yellow |
| pKa | 9.39±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.662 |
| MDL | MFCD01317284 |
1-(2-amino-2-deoxy-β-D-ribofuranosyl)uracil - Introduction
2 '-Amino-D-uridine is an organic compound with the chemical formula C9H13N3O5 and a molecular weight of 243.22g/mol. It is a derivative of uridine in which the 2 '-hydroxyl group is substituted with an amino group.
2 '-Amino-D-uridine have a wide range of uses in biology and medicine. It can be used as a substrate for the synthesis of nucleic acid drugs, for the Study of catalytic ribozymes, and for the modification and labeling of nucleic acid molecules. In addition, it can also be used as a component of biosensors and nucleic acid fluorescent probes.
The method for preparing 2 '-Amino-D-uridine is usually by reacting uridine with a certain concentration of ammonia under appropriate conditions. This reaction may be carried out under basic conditions such that the 2 '-hydroxyl group is substituted with an amino group.
Regarding safety information, due to the specific use and experimental conditions of the 2 '-Amino-D-uridine, its safety needs to be evaluated on a case-by-case basis. Before conducting experiments, the safety data sheet of the compound should be carefully read, and appropriate safety operating guidelines should be followed when handling. At the same time, this compound should be stored in a dry, cool place, and avoid contact with oxidants and strong acids.
2 '-Amino-D-uridine have a wide range of uses in biology and medicine. It can be used as a substrate for the synthesis of nucleic acid drugs, for the Study of catalytic ribozymes, and for the modification and labeling of nucleic acid molecules. In addition, it can also be used as a component of biosensors and nucleic acid fluorescent probes.
The method for preparing 2 '-Amino-D-uridine is usually by reacting uridine with a certain concentration of ammonia under appropriate conditions. This reaction may be carried out under basic conditions such that the 2 '-hydroxyl group is substituted with an amino group.
Regarding safety information, due to the specific use and experimental conditions of the 2 '-Amino-D-uridine, its safety needs to be evaluated on a case-by-case basis. Before conducting experiments, the safety data sheet of the compound should be carefully read, and appropriate safety operating guidelines should be followed when handling. At the same time, this compound should be stored in a dry, cool place, and avoid contact with oxidants and strong acids.
Last Update：2024-04-09 21:11:58
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