1-(2-amino-5-fluorophenyl)ethan-1-one
2-AMINO-5-FLUOROACETOPHENONE
CAS: 2343-25-1
Molecular Formula: C8H8FNO
1-(2-amino-5-fluorophenyl)ethan-1-one - Names and Identifiers
1-(2-amino-5-fluorophenyl)ethan-1-one - Physico-chemical Properties
| Molecular Formula | C8H8FNO |
| Molar Mass | 153.155 |
| Density | 1.201±0.06 g/cm3(Predicted) |
| Melting Point | 64-65 °C |
| Boling Point | 264.2±20.0 °C(Predicted) |
| pKa | 2.37±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
1-(2-amino-5-fluorophenyl)ethan-1-one - Upstream Downstream Industry
1-(2-amino-5-fluorophenyl)ethan-1-one - Introduction
It is an organic compound with a chemical structure of C8H8FNO. The following is a brief description of the properties, uses, methods of manufacture and safety information:
Nature:
-Appearance: White crystalline solid.
-Solubility: It is not easy to dissolve in water, but it can be dissolved in organic solvents such as ethanol and dimethylformamide.
-Melting point: About 115-118 ° C.
-Density: About 1.22g/cm³.
Use:
-Chemical synthesis: It can be used as an intermediate in organic synthesis and can be used to synthesize other compounds.
-Drug research: It can also be used in the field of drug research as a starting point for exploring new drugs.
Method:
There are many preparation methods, and the following is a common method:
-Reaction of p-nitroacetophenone with aminofluorinated molecules under alkaline conditions.
-The specific steps are as follows: P-nitroacetophenone is dissolved in alcohol or ketone solvent, then ammonia water and sodium fluoride are added, the product is separated after a period of reaction, and the pure product can be obtained through crystallization and purification.
Safety Information:
-It has low toxicity, but as an organic compound, it is still necessary to comply with laboratory safety procedures.
-Avoid inhalation of dust, contact with skin and eyes during operation, and use personal protective equipment such as lab gloves, eye goggles and lab coats when necessary.
-It should be operated in a well-ventilated place, and the compound should be stored and disposed of properly to avoid environmental pollution.
-Further safety information and operational recommendations require reference to the compound's safety data sheet (MSDS).
Nature:
-Appearance: White crystalline solid.
-Solubility: It is not easy to dissolve in water, but it can be dissolved in organic solvents such as ethanol and dimethylformamide.
-Melting point: About 115-118 ° C.
-Density: About 1.22g/cm³.
Use:
-Chemical synthesis: It can be used as an intermediate in organic synthesis and can be used to synthesize other compounds.
-Drug research: It can also be used in the field of drug research as a starting point for exploring new drugs.
Method:
There are many preparation methods, and the following is a common method:
-Reaction of p-nitroacetophenone with aminofluorinated molecules under alkaline conditions.
-The specific steps are as follows: P-nitroacetophenone is dissolved in alcohol or ketone solvent, then ammonia water and sodium fluoride are added, the product is separated after a period of reaction, and the pure product can be obtained through crystallization and purification.
Safety Information:
-It has low toxicity, but as an organic compound, it is still necessary to comply with laboratory safety procedures.
-Avoid inhalation of dust, contact with skin and eyes during operation, and use personal protective equipment such as lab gloves, eye goggles and lab coats when necessary.
-It should be operated in a well-ventilated place, and the compound should be stored and disposed of properly to avoid environmental pollution.
-Further safety information and operational recommendations require reference to the compound's safety data sheet (MSDS).
Last Update：2024-04-09 15:18:03
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Product Name: 2-AMINO-5-FLUOROACETOPHENONE Visit Supplier Webpage Request for quotation
CAS: 2343-25-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 2343-25-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for 1-(2-amino-5-fluorophenyl)ethan-1-one
2-Amino-5-fluorobenzoic acid
2-Amino-5-fluorobenzonitrile
Methylmagnesium Bromide
Acetonitrile
Methylmagnesium chloride
2-Amino-5-fluorobenzonitrile
Methylmagnesium Bromide
Acetonitrile
Methylmagnesium chloride