1-(2-aminophenyl)piperazine
2-PIPERAZIN-1-YL-PHENYLAMINE
CAS: 13339-02-1
Molecular Formula: C10H15N3
1-(2-aminophenyl)piperazine - Names and Identifiers
| Name | 2-PIPERAZIN-1-YL-PHENYLAMINE |
| Synonyms | 2-Piperazin-1-ylaniline 2-(1-Piperazino)aniline 2-PIPERAZIN-1-YLANILINE 1-(2-aminophenyl)piperazine 1-(2-AMinophenyl)piperazine 2-PIPERAZIN-1-YL-PHENYLAMINE 2-(Piperazin-1-yl)benzenamine 2-(piperazin-1-yl)benzenamine Benzenamine, 2-(1-piperazinyl)- (9CI) |
| CAS | 13339-02-1 |
| InChI | InChI=1/C10H15N3/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8,11H2 |
1-(2-aminophenyl)piperazine - Physico-chemical Properties
| Molecular Formula | C10H15N3 |
| Molar Mass | 177.25 |
| Density | 1.108g/cm3 |
| Melting Point | 110 °C |
| Boling Point | 344.846°C at 760 mmHg |
| Flash Point | 162.358°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.591 |
| MDL | MFCD03444413 |
1-(2-aminophenyl)piperazine - Risk and Safety
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Class | IRRITANT |
1-(2-aminophenyl)piperazine - Introduction
2-(1-piperazine) aniline, also known as N-benzyl-N'-(1-piperazinyl) aniline, is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: 2-(1-piperazine) aniline is a colorless crystalline solid.
-Solubility: It can be dissolved in some organic solvents and water.
-Chemical properties: 2-(1-piperazine) aniline can undergo a series of organic chemical reactions, such as electrophilic substitution, nitration reaction, etc.
Use:
-Drug research: 2-(1-piperazine) aniline is widely used in the development and synthesis of antiepileptic drugs, anxiolytics, antipsychotics and other drugs in pharmaceutical chemistry.
-Organic synthesis: 2-(1-piperazine) aniline can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
Preparation Method:
- 2-(1-piperazine) aniline can be prepared by the reaction between methyl 1-piperazinyl acetoformate and benzylamine.
Safety Information:
- 2-(1-piperazine) aniline has relatively low toxicity, but it is still necessary to pay attention to safe operation, such as wearing appropriate protective equipment.
-avoid contact with skin and eyes, such as contact, should immediately rinse with plenty of water.
-This compound may cause some harm to the environment, waste and solvents should be properly disposed.
Please note that when using this compound or other chemical substances, you should strictly follow the relevant safety procedures, and evaluate and handle it carefully according to the specific situation.
Nature:
-Appearance: 2-(1-piperazine) aniline is a colorless crystalline solid.
-Solubility: It can be dissolved in some organic solvents and water.
-Chemical properties: 2-(1-piperazine) aniline can undergo a series of organic chemical reactions, such as electrophilic substitution, nitration reaction, etc.
Use:
-Drug research: 2-(1-piperazine) aniline is widely used in the development and synthesis of antiepileptic drugs, anxiolytics, antipsychotics and other drugs in pharmaceutical chemistry.
-Organic synthesis: 2-(1-piperazine) aniline can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
Preparation Method:
- 2-(1-piperazine) aniline can be prepared by the reaction between methyl 1-piperazinyl acetoformate and benzylamine.
Safety Information:
- 2-(1-piperazine) aniline has relatively low toxicity, but it is still necessary to pay attention to safe operation, such as wearing appropriate protective equipment.
-avoid contact with skin and eyes, such as contact, should immediately rinse with plenty of water.
-This compound may cause some harm to the environment, waste and solvents should be properly disposed.
Please note that when using this compound or other chemical substances, you should strictly follow the relevant safety procedures, and evaluate and handle it carefully according to the specific situation.
Last Update：2024-04-09 19:05:46
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CAS: 13339-02-1
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