1-(2-bromo-5-fluorophenyl)ethanone

1-(2-bromo-5-fluorophenyl)ethanone - Names and Identifiers

Name	2'-BROMO-5'-FLUOROACETOPHENONE
Synonyms	2-bromo-5-fluoroacetophenone 2'-BROMO-5'-FLUOROACETOPHENONE Acetophenone, 2'-bromo-5'-fluoro- 1-(2-bromo-5-fluorophenyl)ethanone Ethanone,1-(2-bromo-5-fluorophenyl)- 1-(2-Bromo-5-fluorophenyl)ethan-1-one
CAS	1006-33-3
InChI	InChI=1/C8H6BrFO/c1-5(11)7-4-6(10)2-3-8(7)9/h2-4H,1H3

1-(2-bromo-5-fluorophenyl)ethanone - Physico-chemical Properties

Molecular Formula	C8H6BrFO
Molar Mass	217.04
Density	1.535±0.06 g/cm3(Predicted)
Melting Point	105.672℃
Boling Point	144℃/18mm
Flash Point	105.672°C
Solubility	Soluble in methanol.
Vapor Presure	0.021mmHg at 25°C
Appearance	Solid
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5525
MDL	MFCD07780635

1-(2-bromo-5-fluorophenyl)ethanone - Introduction

2 '-Bromo-5'-fluoroacetophenone is an organic compound whose chemical structure contains a bromine atom and a fluorine atom.

Nature:
-Appearance: colorless or light yellow liquid
-Melting point: about -10 ℃
-Boiling point: about 160-170 ℃
-Density: about 1.49 g/mL
-Solubility: Soluble in most organic solvents such as ethanol, ether and benzene

Use:
2 '-Bromo-5'-fluoroacetophenone has important application value in organic synthesis, and is often used as the raw material of aromatic ketones. It can be used in the synthesis of pharmaceutical intermediates, dyes, spices and other compounds.

Preparation Method:
The preparation of 2 '-bromo-5'-fluoroacetophenone can be obtained by reacting 2-bromo-5-fluorobenzoic acid or a derivative thereof (such as 2-bromo-5-fluorobenzoyl chloride) with an appropriate amount of ethyl acetate or sodium acetate, followed by acidification, hydrolysis and other steps.

Safety Information:
- 2 '-Bromo-5'-fluoroacetophenone is an organic compound with certain toxicity and irritation. During operation and use, appropriate protective measures should be worn, such as protective gloves, protective glasses and protective clothing.
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical help.
-If this compound is inhaled or ingested, the patient should be moved to a fresh air area immediately and seek medical attention immediately.
-This compound should be stored in a cool, dry, well-ventilated place, away from fire and organic matter.

Last Update：2024-04-09 15:17:50