1-(2-chloro-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
2'-chloro-2'-deoxyuridine
CAS: 4753-04-2
Molecular Formula: C9H11ClN2O5
1-(2-chloro-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione - Names and Identifiers
| Name | 2'-chloro-2'-deoxyuridine |
| Synonyms | 2'-CL-DU NSC 526746 2-CHLORO-2-DEOXYURIDINE 2'-CHLORO-2'-DEOXYURIDINE 2'-chloro-2'-deoxyuridine Uridine, 2'-chloro-2'-deoxy- uridine, 2'-chloro-2'-deoxy- 1-(2-chloro-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione 1-((2R,3R,4R,5R)-3-Chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1h,3h)-dione |
| CAS | 4753-04-2 |
| InChI | InChI=1/C9H11ClN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1 |
1-(2-chloro-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione - Physico-chemical Properties
| Molecular Formula | C9H11ClN2O5 |
| Molar Mass | 262.65 |
| Density | 1.67g/cm3 |
| Storage Condition | -20°C |
| Refractive Index | 1.643 |
1-(2-chloro-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione - Introduction
2 '-chloro-2'-deoxyuridine is a chlorine-containing deoxynucleoside. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C9H11ClN2O5
-Molecular weight: 258.65g/mol
-Melting point: 216-220 degrees Celsius
Use:
- 2 '-chloro-2'-deoxyuridine are commonly used in the medical field to treat viral infections and anti-tumor therapies.
-It can act as an inhibitor of viral DNA synthesis in cells and inhibit virus reproduction.
- 2 '-chloro-2'-deoxyuridine is also used as a research reagent in the laboratory to study the related mechanisms of viral infection and DNA synthesis.
Preparation Method:
-A common method for preparing 2 '-chloro-2'-deoxyuridine is to react chlorodeoxyuridine with an alcohol (such as isopropyl alcohol), and then crystallize and purify the product.
Safety Information:
- 2 '-chloro-2'-deoxyuridine may be toxic, so care should be taken when handling and using.
-It is recommended to use appropriate personal protective equipment in the laboratory, such as laboratory gloves and protective glasses.
-Store and handle the compound properly and avoid mixing with other substances.
-Before use, it is best to consult the relevant safety data sheet and instruction manual to learn more about the safety operation guide and risk assessment of the 2 '-chloro-2'-deoxyuridine.
Nature:
-Appearance: White crystalline powder
-Molecular formula: C9H11ClN2O5
-Molecular weight: 258.65g/mol
-Melting point: 216-220 degrees Celsius
Use:
- 2 '-chloro-2'-deoxyuridine are commonly used in the medical field to treat viral infections and anti-tumor therapies.
-It can act as an inhibitor of viral DNA synthesis in cells and inhibit virus reproduction.
- 2 '-chloro-2'-deoxyuridine is also used as a research reagent in the laboratory to study the related mechanisms of viral infection and DNA synthesis.
Preparation Method:
-A common method for preparing 2 '-chloro-2'-deoxyuridine is to react chlorodeoxyuridine with an alcohol (such as isopropyl alcohol), and then crystallize and purify the product.
Safety Information:
- 2 '-chloro-2'-deoxyuridine may be toxic, so care should be taken when handling and using.
-It is recommended to use appropriate personal protective equipment in the laboratory, such as laboratory gloves and protective glasses.
-Store and handle the compound properly and avoid mixing with other substances.
-Before use, it is best to consult the relevant safety data sheet and instruction manual to learn more about the safety operation guide and risk assessment of the 2 '-chloro-2'-deoxyuridine.
Last Update：2024-04-09 20:49:11
