1-(2-chloroethyl)-piperidin
1-(2-Chloroethyl) Piperidine
CAS: 1932-03-2
Molecular Formula: C7H14ClN
1-(2-chloroethyl)-piperidin - Names and Identifiers
1-(2-chloroethyl)-piperidin - Physico-chemical Properties
| Molecular Formula | C7H14ClN |
| Molar Mass | 147.65 |
| Density | 1.008±0.06 g/cm3(Predicted) |
| Melting Point | 229-230 °C(Solv: chloroform (67-66-3); acetone (67-64-1)) |
| Boling Point | 47 °C(Press: 1 Torr) |
| Flash Point | 68.9°C |
| Vapor Presure | 0.545mmHg at 25°C |
| pKa | 8.33±0.10(Predicted) |
| Refractive Index | 1.469 |
1-(2-chloroethyl)-piperidin - Introduction
1-(2-Chloroethyl) Piperidine is an organic compound with the chemical formula C9H12ClN. It is a colorless to pale yellow liquid with a pungent odor. The following is a description of the nature, use, preparation and safety information of 1-(2-Chloroethyl) Piperidine:
Nature:
-Density: 1.05g/cm³
-Boiling point: 149-150 ° C
-Flash point: 43 ° C
-Solubility: Soluble in alcohol and ether, slightly soluble in water
Use:
1-(2-Chloroethyl) Piperidine is widely used in the field of organic synthesis and plays a role as an intermediate and catalyst. Common applications include:
-as a reagent and catalyst in organic synthesis, involved in the manufacture of synthetic drugs, dyes and chemicals.
-for the preparation of organic compounds containing piperidine structures, such as products containing amino or alcohol groups.
Method:
1-(2-Chloroethyl) Piperidine is usually prepared by the following reaction:
1. Reaction: 4-piperidinol and 2-chloroethanol are reacted under alkaline conditions.
2. Product Cleaning: The product is usually purified by extraction, crystallization and purification.
Safety Information:
- 1-(2-chloroform) Piperidine is an irritant and may cause damage to the eyes, skin, and respiratory tract. Wear appropriate personal protective equipment when used.
-Avoid inhaling its vapors and avoid contact with skin and eyes. In case of inadvertent contact, rinse the affected area immediately with plenty of water and seek medical attention.
-in the operation should pay attention to fire and explosion, away from fire and high temperature. Storage should be sealed, away from fire and sunlight, stored in a dry and ventilated place.
-Safe handling and storage in accordance with local codes and regulations. Please read the safety data sheet of the product if necessary.
Nature:
-Density: 1.05g/cm³
-Boiling point: 149-150 ° C
-Flash point: 43 ° C
-Solubility: Soluble in alcohol and ether, slightly soluble in water
Use:
1-(2-Chloroethyl) Piperidine is widely used in the field of organic synthesis and plays a role as an intermediate and catalyst. Common applications include:
-as a reagent and catalyst in organic synthesis, involved in the manufacture of synthetic drugs, dyes and chemicals.
-for the preparation of organic compounds containing piperidine structures, such as products containing amino or alcohol groups.
Method:
1-(2-Chloroethyl) Piperidine is usually prepared by the following reaction:
1. Reaction: 4-piperidinol and 2-chloroethanol are reacted under alkaline conditions.
2. Product Cleaning: The product is usually purified by extraction, crystallization and purification.
Safety Information:
- 1-(2-chloroform) Piperidine is an irritant and may cause damage to the eyes, skin, and respiratory tract. Wear appropriate personal protective equipment when used.
-Avoid inhaling its vapors and avoid contact with skin and eyes. In case of inadvertent contact, rinse the affected area immediately with plenty of water and seek medical attention.
-in the operation should pay attention to fire and explosion, away from fire and high temperature. Storage should be sealed, away from fire and sunlight, stored in a dry and ventilated place.
-Safe handling and storage in accordance with local codes and regulations. Please read the safety data sheet of the product if necessary.
Last Update：2024-04-09 02:00:43
