1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS: 28585-51-5
Molecular Formula: C10H14N2O4S
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one - Names and Identifiers
| Name | 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one |
| Synonyms | 2-THIOTHYMIDINE 2-Thiothymidine Thymidine, 2-thio- 2-Thio-2'-deoxythymidine 2'-deoxy-5-methyl-2-thiouridine 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one |
| CAS | 28585-51-5 |
| InChI | InChI=1/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1 |
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one - Physico-chemical Properties
| Molecular Formula | C10H14N2O4S |
| Molar Mass | 258.29 |
| Density | 1.52g/cm3 |
| Storage Condition | Room Temprature |
| Refractive Index | 1.672 |
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one - Introduction
1-(1-)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (1-(1-)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one) is a nucleoside compound containing a sulfur atom.
Nature:
1-methyl-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one is a white crystalline powder, stable at room temperature. It has high solubility, soluble in water, methanol and dimethyl sulfoxide and other organic solvents.
Use:
1-(1H)-5-methyll-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one has important applications in the field of medicine. It can be used as an antiviral drug and is often used to treat viral infections, such as hepatitis B and AIDS. In addition, 1-(over)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1)-one can also be used to study the chemical synthesis and structure-activity relationship of trans-deoxynucleosides.
Method: The preparation method of 1-(br)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is more complicated and can be synthesized step by step through multi-step reactions. The key steps include enzymatic oxidation, ketonation and thionation of ribose.
Safety Information:
1-()-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is generally safe under normal use conditions, but during the preparation process and the storage and handling of pure products, care should be taken to prevent contact with oxygen and to avoid heating. At the same time, when using and handling, it is necessary to follow the safe operating procedures of the chemical laboratory and be equipped with appropriate personal protective equipment. Specific safety information and precautions should be based on the relevant laboratory operation manual or official documents. The safety and operating procedures of the compound should be understood in detail before use to ensure the safety and accuracy of the operation.
Nature:
1-methyl-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one is a white crystalline powder, stable at room temperature. It has high solubility, soluble in water, methanol and dimethyl sulfoxide and other organic solvents.
Use:
1-(1H)-5-methyll-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one has important applications in the field of medicine. It can be used as an antiviral drug and is often used to treat viral infections, such as hepatitis B and AIDS. In addition, 1-(over)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1)-one can also be used to study the chemical synthesis and structure-activity relationship of trans-deoxynucleosides.
Method: The preparation method of 1-(br)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is more complicated and can be synthesized step by step through multi-step reactions. The key steps include enzymatic oxidation, ketonation and thionation of ribose.
Safety Information:
1-()-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is generally safe under normal use conditions, but during the preparation process and the storage and handling of pure products, care should be taken to prevent contact with oxygen and to avoid heating. At the same time, when using and handling, it is necessary to follow the safe operating procedures of the chemical laboratory and be equipped with appropriate personal protective equipment. Specific safety information and precautions should be based on the relevant laboratory operation manual or official documents. The safety and operating procedures of the compound should be understood in detail before use to ensure the safety and accuracy of the operation.
Last Update：2024-04-09 21:11:58
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Product Name: 2-THIOTHYMIDINE Visit Supplier Webpage Request for quotation
CAS: 28585-51-5
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409
Wechat: 18301782025
CAS: 28585-51-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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