1-(2-methyphenyl)piperazine
1-(o-Tolyl)piperazine
CAS: 39512-51-1
Molecular Formula: C11H16N2
1-(2-methyphenyl)piperazine - Names and Identifiers
| Name | 1-(o-Tolyl)piperazine |
| Synonyms | OTP OTPP 1-(o-Tolyl)piperazine 1-(2-methyphenyl)piperazine 1-(2-methylphenyl)piperazine 1-(2-METHYLPHENYL)PIPERAZINE 1-(o-Methylphenyl)piperazine |
| CAS | 39512-51-1 |
| EINECS | 254-481-9 |
| InChI | InChI=1/C11H16N2/c1-10-4-2-3-5-11(10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 |
1-(2-methyphenyl)piperazine - Physico-chemical Properties
| Molecular Formula | C11H16N2 |
| Molar Mass | 176.26 |
| Density | 1.012±0.06 g/cm3(Predicted) |
| Melting Point | 48-52 °C |
| Boling Point | 136 °C |
| Flash Point | 138.8°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.00104mmHg at 25°C |
| Appearance | Low Melting Mass, Crystals or Crystalline Powder |
| Color | Off-white to light yellow |
| pKa | 8.95±0.10(Predicted) |
| Refractive Index | 1.54 |
1-(2-methyphenyl)piperazine - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R34 - Causes burns R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN3263 |
| HS Code | 29339900 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | III |
1-(2-methyphenyl)piperazine - Introduction
1-(o-Tolyl)piperazine is an organic compound with the chemical formula C11H16N2. It is a white crystalline solid, soluble in alcohol and ether, insoluble in water. It has aromatic properties and a piperazine ring structure.
1-(o-Tolyl)piperazine is an important organic intermediate and pharmaceutical raw material. It is widely used in the synthesis of antipsychotic, antidepressant and anxiolytic drugs. In addition, it can also be used in the production of dyes and dye auxiliaries.
There are various methods for preparing 1-(o-Tolyl)piperazine. A common method is to use toluene as raw material, through the substitution reaction and piperazine condensation reaction, the formation of the target product. The process is generally carried out in a solvent and uses a basic catalyst.
Regarding safety information, 1-(o-Tolyl)piperazine has certain toxicity, and direct contact with skin and inhalation of its dust or vapor should be avoided. Appropriate precautions should be taken during use or storage, such as wearing protective gloves, eye protection and ventilation equipment. If you take it by mistake or accidentally touch it, you should seek medical attention immediately.
1-(o-Tolyl)piperazine is an important organic intermediate and pharmaceutical raw material. It is widely used in the synthesis of antipsychotic, antidepressant and anxiolytic drugs. In addition, it can also be used in the production of dyes and dye auxiliaries.
There are various methods for preparing 1-(o-Tolyl)piperazine. A common method is to use toluene as raw material, through the substitution reaction and piperazine condensation reaction, the formation of the target product. The process is generally carried out in a solvent and uses a basic catalyst.
Regarding safety information, 1-(o-Tolyl)piperazine has certain toxicity, and direct contact with skin and inhalation of its dust or vapor should be avoided. Appropriate precautions should be taken during use or storage, such as wearing protective gloves, eye protection and ventilation equipment. If you take it by mistake or accidentally touch it, you should seek medical attention immediately.
Last Update：2024-04-09 20:52:54
