1-(3,4-dichlorophenyl)methanamine
3,4-Dichlorobenzylamine
CAS: 102-49-8
Molecular Formula: C7H7Cl2N
1-(3,4-dichlorophenyl)methanamine - Names and Identifiers
1-(3,4-dichlorophenyl)methanamine - Physico-chemical Properties
| Molecular Formula | C7H7Cl2N |
| Molar Mass | 176.04 |
| Density | 1.32 g/mL at 25 °C (lit.) |
| Melting Point | 332-333 °C(Solv: N,N-dimethylformamide (68-12-2)) |
| Boling Point | 80-82 °C (0.6 mmHg) |
| Flash Point | >230°F |
| Vapor Presure | 0.0178mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.322 |
| Color | Clear colorless to light yellow |
| BRN | 508818 |
| pKa | 8.56±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.578(lit.) |
1-(3,4-dichlorophenyl)methanamine - Risk and Safety
| Risk Codes | 34 - Causes burns |
| Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29214990 |
| Hazard Note | Irritant/Air Sensitive |
| Hazard Class | 8 |
| Packing Group | III |
1-(3,4-dichlorophenyl)methanamine - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) | |
| introduction | 3, 4-dichlorobenzylamine is a benzylamine compound. Benzylamine compounds are a class of small molecular compounds with simple structure, which widely exist in the biological world and have extremely important physiological and pharmacological activities. They are widely used in the research and development of antibacterial drugs, such as antifungal drugs terbinafine and butenafine. | |
| Preparation | CN200780031748.6 provides a method for preparing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the method comprising reacting 1-cyano-3-octylguanidine or a salt thereof with 3, 4-dichlorobenzylamine or a salt thereof in an ester organic solvent. According to the present invention, the reaction can be carried out at low temperatures using universal equipment, and 1-(3, 4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be prepared in high yield by a safe and simple process. |
Last Update：2024-04-09 02:00:03
