1-(3-Chlorophenyl)-cyclobutanemethanamine

1-(3-Chlorophenyl)-cyclobutanemethanamine - Names and Identifiers

Name	1-[1-(3-chlorophenyl)cyclobutyl]methanamine
Synonyms	LogP OTAVA-BB 1059297 1-(3-Chlorophenyl)-cyclobutanemethanamine (1-(3-Chlorophenyl)cyclobutyl)methylamine [1-(3-chlorophenyl)cyclobutyl]methanamine 1-(3-CHLOROPHENYL)-CYCLOBUTANEMETHANAMINE 1-[1-(3-chlorophenyl)cyclobutyl]methanamine 1-[1-(3-Chlorophenyl)cyclobutyl]methanamine cyclobutanemethanamine, 1-(3-chlorophenyl)- Cyclobutanemethanamine, 1-(3-chlorophenyl)-
CAS	115816-34-7
InChI	InChI=1/C11H14ClN/c12-10-4-1-3-9(7-10)11(8-13)5-2-6-11/h1,3-4,7H,2,5-6,8,13H2

1-(3-Chlorophenyl)-cyclobutanemethanamine - Physico-chemical Properties

Molecular Formula	C11H14ClN
Molar Mass	195.69
Density	1.149
Boling Point	296.1°C at 760 mmHg
Flash Point	161.1°C
Vapor Presure	0.00146mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.57

1-(3-Chlorophenyl)-cyclobutanemethanamine - Introduction

1-(3-Chlorophenyl) cyclobutanomethylamine, chemical formula C10H15ClN, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless or light yellow liquid
-Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons
-Melting point:-5 ℃
-Boiling point: 213-216 ℃
-Density: Approximately 1.05 g/mL
-The compound can exist in two conformers with chirality.

Use:
- 1-(3-Chlorophenyl) cyclobutanemylamine has a central nervous system inhibitory effect similar to anesthetics and can be used as a drug intermediate.
-The compound can also be used in reduction reactions, carboxyl reduction reactions and hydrogenation reactions in organic synthesis.

Method:
The preparation method of -1-(3-chlorophenyl) cyclobutane methylamine usually reacts styrene with phosphorus oxychloride to generate 3-chlorostyrene, and then condenses with cyclobutane methanol under alkaline conditions to obtain the target product.

Safety Information:
-The compound should be handled in a well-ventilated place, avoiding inhalation or contact with skin and eyes.
-Mild irritation, may cause irritation to the eyes, skin and respiratory system, so need to pay attention to protective measures, such as wearing gloves and protective glasses.
-Store and handle the compound properly and follow the relevant safety procedures. In case of accident or discomfort, seek medical help immediately.

Last Update：2024-04-09 19:05:45