1-(3-ThienylMethyl)-piperazine

1-(3-ThienylMethyl)-piperazine - Names and Identifiers

Name	Piperazine, 1-(3-thienylmethyl)- (9CI)
Synonyms	1-(3-thienylmethyl)-Piperazine 1-(3-ThienylMethyl)-piperazine Piperazine,1-(3-thienylMethyl)- 1-(THIOPHEN-3-YLMETHYL)PIPERAZINE Piperazine, 1-(3-thienylmethyl)- (9CI) 1-(thiophen-3-ylMethyl)piperazine 2,2,2-trifluoroacetate
CAS	130288-91-4
InChI	InChI=1/C9H14N2S/c1-6-12-8-9(1)7-11-4-2-10-3-5-11/h1,6,8,10H,2-5,7H2

1-(3-ThienylMethyl)-piperazine - Physico-chemical Properties

Molecular Formula	C9H14N2S
Molar Mass	182.29
Density	1.129g/cm³
Boling Point	277.9°C at 760 mmHg
Flash Point	121.9°C
Vapor Presure	0.00441mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.569

1-(3-ThienylMethyl)-piperazine - Introduction

1-(thiophene-3-methyl) piperazine is an organic compound, its chemical structure contains thiophene and piperazine two ring structure. Its molecular formula is C11H10N2S and its molecular weight is 198.28g/mol.

Nature:
1-(Thiophen-3-methyl) piperazine is a solid, usually white or light yellow crystals. Its melting point is in the range of 175-181°C. The compound is poorly soluble in water and highly soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane.

Use:
1-(thiophene-3-methyl) piperazine is often used as a catalyst or ligand in organic synthesis. It can participate in a variety of organic reactions, such as oxidation, reduction, and the synthesis of carboxylic esters. In addition, the compound can also be used in drug synthesis and materials science research.

Preparation Method:
The common method for preparing 1-(thiophene-3-methyl) piperazine is through the reaction of thiophene and 4-chloropiperazine. The specific step is to first react thiophene with sodium iodide under alkaline conditions to generate 4-iodothiophene, and then react it with 4-chloropiperazine in the presence of sodium carbonate at high temperature to obtain the target product.

Safety Information:
1-(thiophene-3-methyl) piperazine is a chemical, and it is necessary to pay attention to safe operation when using it. It may cause irritation to the eyes, skin and respiratory tract, so contact or inhalation should be avoided. Wear appropriate protective equipment such as gloves, goggles and protective clothing during operation. At the same time, it should be used in a well-ventilated place and stored in a sealed container. In the event of an accident or misuse, you should immediately seek medical attention and consult a professional.

Last Update：2024-04-09 21:11:58