1-(3-aminophenyl)-3-methyl-imidazolidin-2-one
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one
CAS: 517918-82-0
Molecular Formula: C10H13N3O
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one - Names and Identifiers
| Name | 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one |
| Synonyms | 517918-82-0 1-(3-aminophenyl)-3-methylimidazolidin-2-one 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one 2-Imidazolidinone, 1-(3-aminophenyl)-3-methyl- |
| CAS | 517918-82-0 |
| InChI | InChI=1/C10H13N3O/c1-12-5-6-13(10(12)14)9-4-2-3-8(11)7-9/h2-4,7H,5-6,11H2,1H3 |
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one - Physico-chemical Properties
| Molecular Formula | C10H13N3O |
| Density | 1.243g/cm3 |
| Boling Point | 357.8°C at 760 mmHg |
| Flash Point | 170.2°C |
| Vapor Presure | 2.66E-05mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.626 |
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one - Introduction
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one is an organic compound with a chemical formula of C11H12N2O and a molecular weight of 188.23g/mol. The following is a description of the properties, uses, preparation and safety information of the compound.
Nature:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one is a white to pale yellow crystalline powder. It has low solubility and is almost insoluble in water, but has high solubility in organic solvents such as ethanol and dimethyl sulfoxide.
Use:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one has certain application value in the field of drugs and can be used as intermediates for the synthesis of some drug molecules. It is also used as a catalyst in organic synthesis and as a raw material for the synthesis of imidazolidinone derivatives.
Preparation Method:
The preparation of 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one can be carried out by the following steps:
1. In an appropriate solvent, 3-nitrobenzoic acid and methylamine are reacted to obtain methyl 3-aminobenzoate.
2. reacting methyl 3-aminobenzoate with methanol and aluminum trichloride to generate an intermediate imidazolinone compound.
3. Finally, the intermediate compound is reacted with methyl bromide to obtain 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one.
Safety Information:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one has high safety, but the following points still need to be noted:
1. During use, direct contact with skin and eyes should be avoided. In case of contact, rinse immediately with plenty of water and seek medical help.
2. Avoid inhaling the dust and vapor of the compound, and operate in a well-ventilated place.
3. Avoid contact with oxidants and strong acids during storage and handling to prevent dangerous reactions.
Please note that the above information is for reference only. Please follow the relevant chemical safety procedures and materials in actual operation.
Nature:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one is a white to pale yellow crystalline powder. It has low solubility and is almost insoluble in water, but has high solubility in organic solvents such as ethanol and dimethyl sulfoxide.
Use:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one has certain application value in the field of drugs and can be used as intermediates for the synthesis of some drug molecules. It is also used as a catalyst in organic synthesis and as a raw material for the synthesis of imidazolidinone derivatives.
Preparation Method:
The preparation of 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one can be carried out by the following steps:
1. In an appropriate solvent, 3-nitrobenzoic acid and methylamine are reacted to obtain methyl 3-aminobenzoate.
2. reacting methyl 3-aminobenzoate with methanol and aluminum trichloride to generate an intermediate imidazolinone compound.
3. Finally, the intermediate compound is reacted with methyl bromide to obtain 1-(3-aminophenyl)-3-methyl-imidazolidin-2-one.
Safety Information:
1-(3-aminophenyl)-3-methyl-imidazolidin-2-one has high safety, but the following points still need to be noted:
1. During use, direct contact with skin and eyes should be avoided. In case of contact, rinse immediately with plenty of water and seek medical help.
2. Avoid inhaling the dust and vapor of the compound, and operate in a well-ventilated place.
3. Avoid contact with oxidants and strong acids during storage and handling to prevent dangerous reactions.
Please note that the above information is for reference only. Please follow the relevant chemical safety procedures and materials in actual operation.
Last Update：2024-04-09 21:00:56
Supplier List
Spot supply
Product Name: CHEMBRDG-BB 4102967 Visit Supplier Webpage Request for quotationCAS: 517918-82-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: CHEMBRDG-BB 4102967 Visit Supplier Webpage Request for quotationCAS: 517918-82-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History