1-(3-bromo-4-fluorophenyl)ethanone

1-(3-bromo-4-fluorophenyl)ethanone - Names and Identifiers

Name	1-(3-Bromo-4-fluorophenyl)ethan-1-one
Synonyms	144912 3-Bromo-4-fluoroacetophenone 3-BROMO-4-FLUOROACETOPHENONE 3'-BROMO-4'-FLUOROACETOPHENONE 3'-Bromo-4'-fluoroacetophenone 1-(3-BROMO-4-FLUOROPHENYL)ETHANONE 1-(3-bromo-4-fluorophenyl)ethan-1-one 3-Bromo-4-fluorophenyl(methyl) ketone 1-(3-Bromo-4-fluorophenyl)ethan-1-one Ethanone, 1-(3-bromo-4-fluorophenyl)-
CAS	1007-15-4
EINECS	213-750-0
InChI	InChI=1/C8H6BrFO/c1-5(11)6-2-3-8(10)7(9)4-6/h2-4H,1H3

1-(3-bromo-4-fluorophenyl)ethanone - Physico-chemical Properties

Molecular Formula	C8H6BrFO
Molar Mass	217.04
Density	1.5728 (rough estimate)
Melting Point	52-57°C(lit.)
Boling Point	150°C 12mm
Flash Point	>230°F
Appearance	White crystal solid
BRN	3088698
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5450 (estimate)
MDL	MFCD00042466

1-(3-bromo-4-fluorophenyl)ethanone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29147000
Hazard Class	IRRITANT

1-(3-bromo-4-fluorophenyl)ethanone - Introduction

1-(3-bromo-4-fluorophenyl) ethan-1-one, often referred to simply as "bromo-fluoroethanone", is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: Bromo-fluoroethanone is a colorless liquid.
-Chemical formula: C10H8BrFO.
-Molecular weight: 239.08g/mol.
-Solubility: Bromo-fluoroethanone has good solubility in common organic solvents.

Use:
-Bromo-fluoroethanone is an important organic synthesis intermediate, widely used in pharmaceutical and pesticide manufacturing and other fields.
-It can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes.

Preparation Method:
-The preparation of bromo-fluoroethanone is usually achieved by chemical reaction. A common synthesis method is to react 3-bromo-4-fluorophenylacetic acid with an acid chloride (such as phosphorus oxychloride) to obtain the corresponding acid chloride, which is then acylated with ethanone to finally obtain bromo-fluoroethanone.

Safety Information:
-Bromine-fluoroethanone is an organic compound and has certain toxicity. Please wear appropriate protective measures during use, such as gloves and safety glasses, and avoid direct contact with skin and eyes.
-During operation, please pay attention to avoid contact with flammable substances and strong oxidants to prevent fire or explosion.
-During storage, the bromine-fluoroethanone should be stored in a sealed container, avoid contact with air, and placed in a cool, dry, well-ventilated place.
-Disposal of waste related to bromo-fluoroethanone, please follow local regulations to ensure environmental and personal safety.

Last Update：2024-04-09 15:17:50