1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone

1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone - Names and Identifiers

Name	3-Bromo-5-Chloro-2-Hydroxyacetophenone
Synonyms	AKOS BB-6936 2-ACETYL-6-BROMO-4-CHLOROPHENOL 3-Bromo-5-Chloro-2-Hydroxyacetophenone 5-CHLORO-3-BROMO-2-HYDROXYACETOPHENONE 3'-BROMO-5'-CHLORO-2'-HYDROXYACETOPHENONE 1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone 1-(3-Bromo-5-chloro-2-hydroxyphenyl)ethan-1-one 1-(3-broMo-5-chlorophenyl)-2-hydroxyethan-1-one 1-(3-Bromo-5-chloro-2-hydroxyphenyl)ethan-1-one, 2-Acetyl-6-bromo-4-chlorophenol 1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone, 5-Chloro-3-bromo-2-hydroxyacetophenone
CAS	59443-15-1
InChI	InChI=1/C8H6BrClO2/c1-4(11)6-2-5(10)3-7(9)8(6)12/h2-3,12H,1H3

1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone - Physico-chemical Properties

Molecular Formula	C8H6BrClO2
Molar Mass	249.49
Density	1.691±0.06 g/cm3(Predicted)
Melting Point	100-103°C(lit.)
Boling Point	297.8±40.0 °C(Predicted)
Flash Point	133.9°C
Vapor Presure	0.000747mmHg at 25°C
Appearance	powder to crystal
Color	Light orange to Yellow to Green
pKa	8.19±0.23(Predicted)
Storage Condition	2-8°C
Refractive Index	1.604
MDL	MFCD00857068

1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29147000
Hazard Note	Irritant

1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone - Introduction

It is an organic compound with the chemical formula C8H6BrClO2.

Nature:
It is a colorless or pale yellow solid with a bitter taste and a special smell. It has low solubility at room temperature and is soluble in ethanol, phenol and ether. It is stable under light and heat.

Use:
It is often used in organic synthesis as an important intermediate. It can be used to synthesize drugs, fragrances, dyes and other organic compounds. In addition, it can also be used to prepare highly effective photosensitizers, polymers and polymeric materials.

Preparation Method: The preparation of
is usually achieved by keto-alcohol interconversion reaction. The specific steps include reacting 3-bromo-5-chloroacetophenone with an alkaline solution to generate a transition intermediate, which then reacts with an alcohol to generate the target product.

Safety Information:
It is generally relatively safe for humans and the environment under normal conditions of use. But as an organic compound, it can be irritating to the eyes, skin and respiratory system. Wear protective gloves, goggles and appropriate protective equipment during use. In addition, it should be stored in a dry, ventilated and away from fire sources. In case of accidental exposure or ingestion, seek medical attention.

Last Update：2024-04-09 20:52:54