1-(3-chlorophenyl)-2-piperazinone

1-(3-chlorophenyl)-2-piperazinone - Names and Identifiers

Name	1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE
Synonyms	1-(3-Chlorophenyl)piperazin-2-one 1-(3-chlorophenyl)-2-piperazinone 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE 1-(3-Chlorophenyl)-2-piperazinone HCl 1-(3-Chlorophenyl)Piperazin-2-one(HCl)
CAS	183500-70-1
InChI	InChI=1/C10H11ClN2O/c11-8-2-1-3-9(6-8)13-5-4-12-7-10(13)14/h1-3,6,12H,4-5,7H2

1-(3-chlorophenyl)-2-piperazinone - Physico-chemical Properties

Molecular Formula	C10H11ClN2O
Molar Mass	210.66
Density	1.268g/cm³
Boling Point	443.887°C at 760 mmHg
Flash Point	222.255°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.574

1-(3-chlorophenyl)-2-piperazinone - Introduction

1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE is an organic compound with the formula C11H8ClNO, containing a chlorophenyl group and a piperazine ring in the structure. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-(3-chroo-phenyl)-PIPERAZIN-2-ONE is a white crystalline solid with a high melting and boiling point. It is difficult to dissolve in solvents, but it is soluble in some organic solvents.

Use:
1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE has antipsychotic activity and can be used to treat schizophrenia and other psychiatric disorders. As an antagonist of amine neurotransmitters, it can regulate the signal transmission of neurotransmitters, thus inhibiting abnormal behavior and thinking.

Method:
1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE can be achieved by introducing a chlorophenyl group on the piperazine ring and under appropriate conditions. The specific synthesis method includes adding 3-chlorobenzoyl chloride to piperazine and heating to react to obtain the target product, followed by crystallization and purification.

Safety Information:

Last Update：2024-04-10 22:29:15