1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone

1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone - Names and Identifiers

Name	1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone
Synonyms	1-[4-(4-methylimidazol-1-yl)phenyl]ethanone 1-[4-(4-methyl-1-imidazolyl)phenyl]ethanone 1-[4-(4-Methyl-1H-imidazol-1-yl)phenyl]ethanone 1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone ethanone, 1-[4-(4-methyl-1H-imidazol-1-yl)phenyl]- 1-(4-(4-methyl-1H-imidazol-1-yl)phenyl)ethan-1-one
CAS	142161-53-3
InChI	InChI=1/C12H12N2O/c1-9-7-14(8-13-9)12-5-3-11(4-6-12)10(2)15/h3-8H,1-2H3

1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone - Physico-chemical Properties

Molecular Formula	C12H12N2O
Molar Mass	200.24
Density	1.11
Boling Point	375.253°C at 760 mmHg
Flash Point	180.747°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.585

1-(4-(4-Methyl-1H-imidazol-1-yl)phenyl)ethanone - Introduction

1-(4-(4-Methyl-1H-imidazol-1-yl) phenyl) ethanone, chemical formula C15H14N2O, molecular weight 250.29. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-(4-(4-Methyl-1H-imidazol-1-yl) phenyl) ethanone is an organic compound and appears as a white crystal or crystalline powder. It has good solubility at room temperature and can be dissolved in many organic solvents, such as methanol, alcohols and ether solvents.

Use:
1-(4-(4-methyl-1H-imidazol-1-yl) phenyl) ethanone is an important organic synthesis intermediate compound, which can be used to synthesize a variety of drugs, dyes and photosensitive substances. It is one of the important intermediates in the synthesis of many famous drugs, such as the non-steroidal anti-inflammatory drug Flurbiprofen.

Preparation Method:
There are various methods for preparing 1-(4-(4-methyl -1H-imidazol-1-yl) phenyl) ethanone, but the commonly used method is to use benzoic acid and methyl -1H-imidazole under alkaline conditions to form an imine structure, and then introduce acetyl group through acylation reaction to obtain the target compound.

Safety Information:
1-(4-(4-methyl-1H-imidazol-1-yl) phenyl) ethanone has low toxicity, and has good stability and operability. But as an organic compound, it still has a certain potential danger. Use should pay attention to the following safety measures:
-Avoid direct contact with skin and eyes. If exposed, rinse immediately with plenty of water.
-Good ventilation conditions should be provided during operation to avoid inhalation of compound vapors.
-Store it in a sealed container, away from fire and oxidizing agents.
-Use personal protective equipment such as lab gloves and goggles during handling and storage.

Last Update：2024-04-09 02:00:42