1-(4-Chloro-phenyl)-cyclopropylamine

1-(4-Chloro-phenyl)-cyclopropylamine - Names and Identifiers

Name	1-(4-chlorophenyl)cyclopropanamine
Synonyms	LogP 1-(4-Chlorphenyl)cyclopropanamin 1-(4-CHLOROPHENYL)CYCLOPROPANAMINE 1-(4-chlorophenyl)cyclopropanamine 1-(4-CHLORO-PHENYL)-CYCLOPROPYLAMINE 1-(4-Chloro-phenyl)-cyclopropylamine 1-(4-chlorophenyl)-1-cyclopropanamine cyclopropanamine, 1-(4-chlorophenyl)- 1-(4-Chlorophenyl)cyclopropan-1-amine Cyclopropanamine, 1-(4-chlorophenyl)-
CAS	72934-36-2
InChI	InChI=1/C9H10ClN/c10-8-3-1-7(2-4-8)9(11)5-6-9/h1-4H,5-6,11H2

1-(4-Chloro-phenyl)-cyclopropylamine - Physico-chemical Properties

Molecular Formula	C9H10ClN
Molar Mass	167.64
Density	1.238±0.06 g/cm3(Predicted)
Melting Point	27 °C
Boling Point	118-120 °C(Press: 12 Torr)
Flash Point	100.8°C
Vapor Presure	0.0326mmHg at 25°C
pKa	7.57±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.605

1-(4-Chloro-phenyl)-cyclopropylamine - Risk and Safety

Hazard Class

IRRITANT

1-(4-Chloro-phenyl)-cyclopropylamine - Introduction

1-(4-chlorophenyl)cyclopropanamine is an organic compound with the chemical formula C9H10ClN. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(4-chlorophenyl)cyclopropanamine is a white crystalline solid. It has a high melting point and boiling point and is soluble in some organic solvents, such as ethanol and dichloromethane. It is an organic amine compound with amine and phenyl functional groups. Its molecular structure contains a cyclopropane ring with a chlorophenyl group attached to the ring.

Use:
1-(4-chlorophenyl)cyclopropanamine is widely used as a synthetic intermediate in medicinal chemistry. It can be used to produce antidepressants, antipsychotics, sedatives and antiemetics. It can also be used to research and develop new organic compounds.

Preparation Method:
1-(4-chlorophenyl)cyclopropanamine can be synthesized from benzoic acid and cycloacetone as starting materials. First, benzoic acid and cycloacetone undergo an acid-catalyzed reaction to form cycloacetonate benzoate. Then, cycloacetonyl benzoate is reduced to 1-(4-chlorophenyl)cyclopropanamine by a hydrogenation reduction reaction.

Safety Information:
1-(4-chlorophenyl)cyclopropanamine is an organic synthesis intermediate, which may have certain risks to operators. It should be properly stored away from ignition and oxidizing agents. Wear protective glasses, gloves and lab coat during use. At the same time, should avoid inhalation, contact with the skin or ingestion. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:11:58