1-(4-Chlorophenyl)piperazine
1-(4-Chlorophenyl)piperazine
CAS: 38212-33-8
Molecular Formula: C10H13ClN2
1-(4-Chlorophenyl)piperazine - Names and Identifiers
| Name | 1-(4-Chlorophenyl)piperazine |
| Synonyms | AKOS BBS-00003582 TIMTEC-BB SBB003580 RARECHEM AH CK 0072 1-(4-CHLORPHENYL)PIPERAZINE 1-(4-Chlorophenyl)Piperazone 1-(4-Chlorophenyl)piperazine 1-(4-CHLOROPHENYL)PIPERAZINE |
| CAS | 38212-33-8 |
| InChI | InChI=1/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 |
| InChIKey | UNEIHNMKASENIG-UHFFFAOYSA-N |
1-(4-Chlorophenyl)piperazine - Physico-chemical Properties
| Molecular Formula | C10H13ClN2 |
| Molar Mass | 196.68 |
| Density | 1.1428 (rough estimate) |
| Melting Point | 76-79°C |
| Boling Point | 113°C/0.27mm |
| Flash Point | 157.2°C |
| Water Solubility | It is soluble in water. |
| Vapor Presure | 0.000113mmHg at 25°C |
| BRN | 150981 |
| pKa | 8.88±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.5749 (estimate) |
1-(4-Chlorophenyl)piperazine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-34 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
1-(4-Chlorophenyl)piperazine - Introduction
1-(4-Chlorophenyl)piperazine is an organic compound with the chemical formula of C≡alcoH≡ClN₂. It is a derivative of piperazine in which the position of one of the benzene rings is replaced by a chlorine atom.
Nature:
1-(4-Chlorophenyl)piperazine is a white crystalline solid with a pungent odor. It can be dissolved in many organic solvents, such as ethanol, methanol and dichloromethane.
Use:
1-(4-Chlorophenyl)piperazine has certain applications in the field of medicine. It is used as an intermediate in central nervous system drugs and is commonly used in the synthesis of anxiolytic, antidepressant and antipsychotic drugs.
Preparation Method:
1-(4-Chlorophenyl)piperazine can be prepared by adding p-chlorophenyl carbonyl chloride or p-chlorophenyl acetyl chloride to piperazine, and reacting under alkaline conditions to generate the product, which is then crystallized and purified.
Safety Information:
1-(4-Chlorophenyl)piperazine are generally relatively safe under normal use and storage conditions. However, as with all chemicals, proper laboratory practices should be followed to avoid inhalation, ingestion, or skin contact. It can cause irritation and damage to the eyes, skin and respiratory system. Wear appropriate protective equipment such as gloves, goggles, and lab coats when handling this compound. In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
Nature:
1-(4-Chlorophenyl)piperazine is a white crystalline solid with a pungent odor. It can be dissolved in many organic solvents, such as ethanol, methanol and dichloromethane.
Use:
1-(4-Chlorophenyl)piperazine has certain applications in the field of medicine. It is used as an intermediate in central nervous system drugs and is commonly used in the synthesis of anxiolytic, antidepressant and antipsychotic drugs.
Preparation Method:
1-(4-Chlorophenyl)piperazine can be prepared by adding p-chlorophenyl carbonyl chloride or p-chlorophenyl acetyl chloride to piperazine, and reacting under alkaline conditions to generate the product, which is then crystallized and purified.
Safety Information:
1-(4-Chlorophenyl)piperazine are generally relatively safe under normal use and storage conditions. However, as with all chemicals, proper laboratory practices should be followed to avoid inhalation, ingestion, or skin contact. It can cause irritation and damage to the eyes, skin and respiratory system. Wear appropriate protective equipment such as gloves, goggles, and lab coats when handling this compound. In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
Last Update：2024-04-09 20:45:29
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Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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Product Name: 1-(4-Chlorophenyl)Piperazine Visit Supplier Webpage Request for quotationCAS: 38212-33-8
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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