1-(4-FLUOROPHENYL)-2-NITROETHENE

1-(4-FLUOROPHENYL)-2-NITROETHENE - Names and Identifiers

Name	p-fluoro-β-nitrostyrene
Synonyms	p-fluoro-β-nitrostyrene p-Fluoro-β-nitrostyrene p-fluoro-beta-nitrostyrene p-fluoro-beta-nitro-styren 1-Fluoro-4-(2-nitrovinyl)benzene 1-(4-FLUOROPHENYL)-2-NITROETHENE 1-(4-FLUOROPHENYL)-2-NITROETHYLENE 1-FLUORO-4-(2-NITRO-VINYL)-BENZENE 1-Fluoro-4-(2-nitrovinyl)benzene, 1-Fluoro-4-(2-nitroethenyl)benzene
CAS	706-08-1
EINECS	211-891-2
InChI	InChI=1/C8H6FNO2/c9-8-3-1-7(2-4-8)5-6-10(11)12/h1-6H/b6-5+
InChIKey	VRFSQVFSQAYHRU-UHFFFAOYSA-N

1-(4-FLUOROPHENYL)-2-NITROETHENE - Physico-chemical Properties

Molecular Formula	C8H6FNO2
Molar Mass	167.14
Density	1.276±0.06 g/cm3(Predicted)
Melting Point	100-102°C
Boling Point	254.5±15.0 °C(Predicted)
Water Solubility	Slightly soluble in water.
Appearance	Crystalline Solid
Color	Pale yellow
BRN	2208372
Storage Condition	Room Temprature
MDL	MFCD00024824

1-(4-FLUOROPHENYL)-2-NITROETHENE - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed
Safety Description	S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S39 - Wear eye / face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN 2811 6.1/PG 1
WGK Germany	3
RTECS	WL4800000
Hazard Note	Irritant
Hazard Class	6.1

1-(4-FLUOROPHENYL)-2-NITROETHENE - Reference Information

overview

1-(4-fluorophenyl)-2-nitroethylene belongs to nitroolefins and is a class of bioactive compounds. it has important applications in antibacterial, anticancer, antitumor or cell signaling factors. The new antibiotic lajollamycin containing nitroolefin structure isolated from marine sediments exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcal activity. It can also inhibit the growth of mouse melanoma cells. At the same time, nitroolefins can also be used for Michael addition, especially asymmetric Michael addition; the cycloaddition reaction of nitroolefins can be used to construct various cyclic compounds containing nitrogen substituents; through hydrogenation reduction It can also convert nitroolefins into various useful nitrogen-containing compounds.

application

1-(4-fluorophenyl)-2-nitroethylene belongs to nitroolefins and is a class of bioactive compounds. it has important applications in antibacterial, anticancer, antitumor or as cell signaling factors.

Last Update：2024-04-10 22:30:50