1-(4-Hydroxyphenyl)-1H-imidazole - Names and Identifiers
1-(4-Hydroxyphenyl)-1H-imidazole - Physico-chemical Properties
Molecular Formula | C9H8N2O
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Molar Mass | 160.17 |
Density | 1.1846 (rough estimate) |
Melting Point | 204-206°C(lit.) |
Boling Point | 286.07°C (rough estimate) |
Flash Point | 165.9°C |
Vapor Presure | 2.14E-05mmHg at 25°C |
Appearance | Fine Crystalline Powder |
Color | Light brown-gray to brown-beige |
BRN | 509999 |
pKa | 9.36±0.26(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.5570 (estimate) |
MDL | MFCD00005281 |
1-(4-Hydroxyphenyl)-1H-imidazole - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S22 - Do not breathe dust.
|
WGK Germany | 3 |
HS Code | 29332990 |
1-(4-Hydroxyphenyl)-1H-imidazole - Introduction
4-(Imidazol-1-yl) phenol, chemical formula C12H10N2O, is an organic compound, also known as imidazolophenol.
Properties: 4-(imidazol-1-yl) phenol is a white crystalline solid, soluble in organic solvents such as ethanol and chloroform, and slightly soluble in water. It has a fragrant smell.
Uses: 4-(imidazol-1-yl) phenol has a variety of uses in the chemical field. It can be used as an intermediate in organic synthesis for the preparation of other organic compounds. In addition, it can also be used as dyes, photosensitizers and pharmaceutical raw materials in the field of medicine.
Preparation Method: A common method for preparing 4-(imidazol-1-yl) phenol is to react phenol with imidazole in the presence of a base. The specific steps are that phenol and imidazole are added to a solvent, a base catalyst is added at a higher temperature, the reaction is stirred for a period of time, and the product is obtained by cooling and crystallization. 4-(imidazol-1-yl) phenol of high purity can be obtained by purification and crystallization.
Safety information: 4-(imidazol-1-yl) phenol requires attention to its safe handling and storage. Due to its irritating and toxic nature, contact with skin or inhalation may cause allergic reactions and respiratory irritation. Therefore, the operation should wear protective gloves, masks and goggles, and in a well-ventilated place. It should be stored in a dry, cool, closed container, away from fire and oxidizing agents. If an accident occurs, immediately rinse the affected area with plenty of water and seek medical help.
Last Update:2024-04-09 21:04:16