1-(4-Methoxyphenyl-Piperazine)
1-(4-Methoxyphenyl-Piperazine)
CAS: 38212-30-5
Molecular Formula: C11H16N2O
1-(4-Methoxyphenyl-Piperazine) - Names and Identifiers
| Name | 1-(4-Methoxyphenyl-Piperazine) |
| Synonyms | 1-(4-methoxyphenyl)piperazine 4-(4-Methoxyphenyl)piperazine 1-(4-Methoxyphenyl)piperazine 1-(4-Methoxyphenyl-Piperazine) N-(4-methoxy phenyl) piperazine PARA METHOXY PHENYL PIPERAZINE HCL PARA METHOXY PHENYL PIPERAZINE HYDROCHLORIDE 1-(4-METHOXYLPHENYL)-PIPERAZINE MONOHYDROCHLORIDE |
| CAS | 38212-30-5 |
| EINECS | 253-829-7 |
| InChI | InChI=1/C11H16N2O/c1-14-11-4-2-10(3-5-11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 |
1-(4-Methoxyphenyl-Piperazine) - Physico-chemical Properties
| Molecular Formula | C11H16N2O |
| Molar Mass | 192.26 |
| Density | 1.0529 (rough estimate) |
| Melting Point | 42-47 °C (lit.) |
| Boling Point | 130 °C |
| Flash Point | >230°F |
| Water Solubility | soluble in water, methanol and toluene |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 6.8E-05mmHg at 25°C |
| Appearance | Crystalline Low Melting Solid |
| Color | Light yellow to amber |
| BRN | 156736 |
| pKa | 8.98±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
| Sensitive | Air Sensitive |
| Refractive Index | 1.5750 (estimate) |
1-(4-Methoxyphenyl-Piperazine) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S28A - |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-34 |
| HS Code | 29335990 |
| Hazard Note | Irritant |
1-(4-Methoxyphenyl-Piperazine) - Introduction
1-(4-Methoxyphenyl-Piperazine) is an organic compound with the chemical formula of C≡alcoH≡N₂ O, which is a white crystalline solid.
Nature:
-Appearance: White crystalline solid
-Melting point: approximately 188-190°C
-Solubility: Soluble in ethanol and dichloromethane
Use:
-Drug research: 1-(4-Methoxyphenyl-Piperazine) is a compound skeleton, which is widely used in drug research and development, especially for the design and synthesis of new antipsychotic, antidepressant and anxiolytic drugs, etc.
Preparation Method: 1-(4-Methoxyphenyl-Piperazine) can be synthesized by the following method:
-First, 4-methoxyaniline and tert-butanol are synthesized into tert-butyl 4-methoxyphenyl carboxylate.
-Then, methylaniline is reacted with tert-butyl 4-methoxyphenylcarboxylate to obtain 1-(4-Methoxyphenyl-Piperazine).
Safety Information:
- 1-(4-Methoxyphenyl-Piperazine) is less toxic and dangerous, but it is still necessary to follow safe operating procedures and avoid inhalation, ingestion or contact with skin.
-Wear appropriate personal protective equipment such as gloves, goggles and masks during operation.
-In the event of accidental leakage, use suitable absorbent materials for cleaning and disposal. Observe local regulations when discarding.
Nature:
-Appearance: White crystalline solid
-Melting point: approximately 188-190°C
-Solubility: Soluble in ethanol and dichloromethane
Use:
-Drug research: 1-(4-Methoxyphenyl-Piperazine) is a compound skeleton, which is widely used in drug research and development, especially for the design and synthesis of new antipsychotic, antidepressant and anxiolytic drugs, etc.
Preparation Method: 1-(4-Methoxyphenyl-Piperazine) can be synthesized by the following method:
-First, 4-methoxyaniline and tert-butanol are synthesized into tert-butyl 4-methoxyphenyl carboxylate.
-Then, methylaniline is reacted with tert-butyl 4-methoxyphenylcarboxylate to obtain 1-(4-Methoxyphenyl-Piperazine).
Safety Information:
- 1-(4-Methoxyphenyl-Piperazine) is less toxic and dangerous, but it is still necessary to follow safe operating procedures and avoid inhalation, ingestion or contact with skin.
-Wear appropriate personal protective equipment such as gloves, goggles and masks during operation.
-In the event of accidental leakage, use suitable absorbent materials for cleaning and disposal. Observe local regulations when discarding.
Last Update：2024-04-09 21:01:54
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Multiple SpecificationsSpot supply
Product Name: Posaconazole Impurity 54 Visit Supplier Webpage Request for quotationCAS: 38212-30-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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