1-(4-Pyridyl)piperidine
1-(4-Pyridyl)piperidine
CAS: 2767-90-0
Molecular Formula: C10H14N2
1-(4-Pyridyl)piperidine - Names and Identifiers
| Name | 1-(4-Pyridyl)piperidine |
| Synonyms | 4-piperidylpyridine 4-PIPERIDINO PYRIDINE 1-Pyridin-4-piperidine 1-(4-Pyridyl)piperidine 4-(1-Piperidyl)pyridine 4-(Piperidin-1-yl)pyridine (Pyridine,4-(1-piperidinyl)-) |
| CAS | 2767-90-0 |
| EINECS | 220-447-7 |
| InChIKey | MTPBUCCXRGSDCR-UHFFFAOYSA-N |
1-(4-Pyridyl)piperidine - Physico-chemical Properties
| Molecular Formula | C10H14N2 |
| Molar Mass | 162.23 |
| Density | 1.047±0.06 g/cm3(Predicted) |
| Melting Point | 78-83°C |
| Boling Point | 164 °C(Press: 13 Torr) |
| pKa | 10.88±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
1-(4-Pyridyl)piperidine - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2923 6.1(8) / PGIII |
| WGK Germany | 3 |
1-(4-Pyridyl)piperidine - Introduction
1-(4-Pyridyl)piperidine is an organic compound with the chemical formula C10H14N2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1-(4-Pyridyl)piperidine is a colorless to light yellow liquid.
-Solubility: Soluble in most organic solvents, such as ethanol, acetone and dimethylformamide.
-melting point and boiling point: melting point is about -35 ℃, boiling point is about 170 ℃.
-Aroma: 1-(4-Pyridyl)piperidine has a special smell.
Use:
- 1-(4-Pyridyl)piperidine can be used as an intermediate and catalyst in organic synthesis.
-It is often used in N-substitution reactions in organic synthesis, for example, as an organic acid catalyst in chemical reactions, such as esterification and acylation.
-The compound also has some applications in the pharmaceutical field, such as as an intermediate for pharmaceutical ingredients.
Method:
- 1-(4-Pyridyl)piperidine can be obtained by reacting 1-pyridine with piperidine under appropriate conditions. The reaction conditions may include a suitable solvent, a suitable temperature and a catalyst.
Safety Information:
- 1-(4-Pyridyl)piperidine is generally considered to be a relatively safe compound.
-However, appropriate laboratory procedures and safety measures, such as wearing appropriate protective equipment (gloves, goggles, etc.), should still be followed.
-When performing any chemical operation, follow the relevant safety guidelines and avoid contact with skin and eyes.
Nature:
-Appearance: 1-(4-Pyridyl)piperidine is a colorless to light yellow liquid.
-Solubility: Soluble in most organic solvents, such as ethanol, acetone and dimethylformamide.
-melting point and boiling point: melting point is about -35 ℃, boiling point is about 170 ℃.
-Aroma: 1-(4-Pyridyl)piperidine has a special smell.
Use:
- 1-(4-Pyridyl)piperidine can be used as an intermediate and catalyst in organic synthesis.
-It is often used in N-substitution reactions in organic synthesis, for example, as an organic acid catalyst in chemical reactions, such as esterification and acylation.
-The compound also has some applications in the pharmaceutical field, such as as an intermediate for pharmaceutical ingredients.
Method:
- 1-(4-Pyridyl)piperidine can be obtained by reacting 1-pyridine with piperidine under appropriate conditions. The reaction conditions may include a suitable solvent, a suitable temperature and a catalyst.
Safety Information:
- 1-(4-Pyridyl)piperidine is generally considered to be a relatively safe compound.
-However, appropriate laboratory procedures and safety measures, such as wearing appropriate protective equipment (gloves, goggles, etc.), should still be followed.
-When performing any chemical operation, follow the relevant safety guidelines and avoid contact with skin and eyes.
Last Update：2024-04-09 20:45:29
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CAS: 2767-90-0
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