1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide
1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide
CAS: 950256-12-9
Molecular Formula: C12H16BrNO2S
1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide - Names and Identifiers
| Name | 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide |
| Synonyms | 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide Benzenemethanesulfonamide, 4-bromo-N-cyclopentyl- |
| CAS | 950256-12-9 |
1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide - Physico-chemical Properties
| Molecular Formula | C12H16BrNO2S |
| Molar Mass | 318.23 |
1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide - Introduction
1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or yellowish solid
-Molecular formula: C13H17BrNO2S
-Molecular weight: 321.25g/mol
-Melting point: about 100-102 degrees Celsius
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and acetonitrile
Use:
- 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide can be used as a reagent in pharmaceutical research and synthesis. It is often used as an intermediate in the synthesis of biologically active compounds or drug molecules.
-It can also be used as a regulator of G protein-coupled receptors (GPCR) in the field of medicine.
Preparation Method:
The preparation of 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide is usually carried out by the following steps:
1. Condensation of 4-bromobenzaldehyde and cyanomethanesulfonic acid ester to generate 4-bromobenzene methanesulfonic acid ester.
2.4-Bromophenyl methyl sulfonate was reacted with cyclopentylamine, and 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide was finally obtained by deprotection reaction, oxidation reaction and n-butyl bromination reaction.
Safety Information:
- 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide should avoid contact with strong oxidants and avoid moisture during use or storage.
-May cause irritation by inhalation, ingestion, or skin contact. Avoid contact with skin, eyes, and respiratory tract.
-Wear suitable personal protective equipment, such as protective gloves, safety glasses and protective masks.
-When using or disposing, please follow local regulations and safe operation guidelines.
Nature:
-Appearance: Colorless or yellowish solid
-Molecular formula: C13H17BrNO2S
-Molecular weight: 321.25g/mol
-Melting point: about 100-102 degrees Celsius
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and acetonitrile
Use:
- 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide can be used as a reagent in pharmaceutical research and synthesis. It is often used as an intermediate in the synthesis of biologically active compounds or drug molecules.
-It can also be used as a regulator of G protein-coupled receptors (GPCR) in the field of medicine.
Preparation Method:
The preparation of 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide is usually carried out by the following steps:
1. Condensation of 4-bromobenzaldehyde and cyanomethanesulfonic acid ester to generate 4-bromobenzene methanesulfonic acid ester.
2.4-Bromophenyl methyl sulfonate was reacted with cyclopentylamine, and 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide was finally obtained by deprotection reaction, oxidation reaction and n-butyl bromination reaction.
Safety Information:
- 1-(4-bromophenyl)-N-cyclopentylmethanesulfonamide should avoid contact with strong oxidants and avoid moisture during use or storage.
-May cause irritation by inhalation, ingestion, or skin contact. Avoid contact with skin, eyes, and respiratory tract.
-Wear suitable personal protective equipment, such as protective gloves, safety glasses and protective masks.
-When using or disposing, please follow local regulations and safe operation guidelines.
Last Update：2024-04-09 02:00:49
