1-(4-chloro-3-methylphenyl)ethanone
4'-Chloro-3'-methylacetophenone
CAS: 37074-39-8
Molecular Formula: C9H9ClO
1-(4-chloro-3-methylphenyl)ethanone - Names and Identifiers
| Name | 4'-Chloro-3'-methylacetophenone |
| Synonyms | Chloro-3-Methylacetophen 3-Methyl-4-chloroacetophenone 4-CHLORO-3-METHYLACETOPHENONE 4'-Chloro-3'-methylacetophenone 3'-methyl-4'-chloroacetophenone 1-(4-chloro-3-methylphenyl)ethanone 1-(4-Chloro-3-methylphenyl)ethanone 1-(4-CHLORO-3-METHYLPHENYL)ETHAN-1-ONE Ethanone, 1-(4-chloro-3-methylphenyl)- ethanone, 1-(4-chloro-3-methylphenyl)- |
| CAS | 37074-39-8 |
| InChI | InChI=1/C9H9ClO/c1-6-5-8(7(2)11)3-4-9(6)10/h3-5H,1-2H3 |
1-(4-chloro-3-methylphenyl)ethanone - Physico-chemical Properties
| Molecular Formula | C9H9ClO |
| Molar Mass | 168.62 |
| Density | 1.15 |
| Melting Point | 56-57 °C |
| Boling Point | 104-105°C 0,4mm |
| Flash Point | 104-105°C/0.4mm |
| Vapor Presure | 0.0105mmHg at 25°C |
| BRN | 774639 |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.555 |
1-(4-chloro-3-methylphenyl)ethanone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/38 - Irritating to eyes and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29147000 |
1-(4-chloro-3-methylphenyl)ethanone - Introduction
4 '-Chloro-3'-methylacetophenone, also known as 4 '-Chloro-3'-methylacetophenone, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4 '-Chloro-3'-methylacetophenone is a white crystalline solid.
-Melting point: Its melting point is 80-82 degrees Celsius.
-Solubility: It has good solubility in some organic solvents, such as ethanol, ether and petroleum ether.
Use:
-Chemical synthesis: 4 '-Chloro-3'-methylacetophenone can be used as an organic synthesis intermediate for the synthesis of other compounds.
-Pharmaceutical research: This compound is often used in pharmaceutical research and development, especially in the process of synthesizing drugs.
-Fragrance additive: It can also be used as a fragrance additive to add a specific taste to perfumes and other products.
Preparation Method:
- 4 '-Chloro-3'-methylacetophenone is generally prepared by a chloroalkylation reaction. The specific steps include reacting 3-methyl acetophenone with chlorine gas under appropriate solvent conditions, and obtaining the target product through appropriate purification, crystallization and other steps.
Safety Information:
- 4 '-Chloro-3'-methylacetophenone is less toxic and dangerous, but it is still necessary to pay attention to safe operation.
-Wear appropriate protective equipment such as chemical protective gloves and goggles when using and handling this compound.
-Avoid inhaling its dust or touching the skin to avoid irritation or allergic reactions.
-Follow appropriate safety practices and specifications when storing and handling this compound.
-In case of accidental exposure or discomfort, seek medical attention immediately.
Nature:
-Appearance: 4 '-Chloro-3'-methylacetophenone is a white crystalline solid.
-Melting point: Its melting point is 80-82 degrees Celsius.
-Solubility: It has good solubility in some organic solvents, such as ethanol, ether and petroleum ether.
Use:
-Chemical synthesis: 4 '-Chloro-3'-methylacetophenone can be used as an organic synthesis intermediate for the synthesis of other compounds.
-Pharmaceutical research: This compound is often used in pharmaceutical research and development, especially in the process of synthesizing drugs.
-Fragrance additive: It can also be used as a fragrance additive to add a specific taste to perfumes and other products.
Preparation Method:
- 4 '-Chloro-3'-methylacetophenone is generally prepared by a chloroalkylation reaction. The specific steps include reacting 3-methyl acetophenone with chlorine gas under appropriate solvent conditions, and obtaining the target product through appropriate purification, crystallization and other steps.
Safety Information:
- 4 '-Chloro-3'-methylacetophenone is less toxic and dangerous, but it is still necessary to pay attention to safe operation.
-Wear appropriate protective equipment such as chemical protective gloves and goggles when using and handling this compound.
-Avoid inhaling its dust or touching the skin to avoid irritation or allergic reactions.
-Follow appropriate safety practices and specifications when storing and handling this compound.
-In case of accidental exposure or discomfort, seek medical attention immediately.
Last Update：2024-04-09 02:00:45
