1-(4-chlorophenyl)-3-phenylthiourea
1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA
CAS: 7392-67-8
Molecular Formula: C13H11ClN2S
1-(4-chlorophenyl)-3-phenylthiourea - Names and Identifiers
| Name | 1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA |
| Synonyms | 1-(4-chlorophenyl)-3-phenylthiourea 1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA Thiourea, N-(4-chlorophenyl)-N'-phenyl- |
| CAS | 7392-67-8 |
1-(4-chlorophenyl)-3-phenylthiourea - Physico-chemical Properties
| Molecular Formula | C13H11ClN2S |
| Molar Mass | 262.76 |
| Density | 1.385±0.06 g/cm3(Predicted) |
| Melting Point | 152°C |
| Boling Point | 375.7±44.0 °C(Predicted) |
| pKa | 12.14±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD00022116 |
1-(4-chlorophenyl)-3-phenylthiourea - Risk and Safety
| Hazard Class | IRRITANT |
1-(4-chlorophenyl)-3-phenylthiourea - Upstream Downstream Industry
| Downstream Products | 1,2,3-TRIPHENYLGUANIDINE |
1-(4-chlorophenyl)-3-phenylthiourea - Introduction
1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA is an organic compound whose chemical formula is C13H10ClN3S. It is a white crystalline solid with low solubility.
One of the main uses of this compound is as an antithyroid agent. It can suppress the symptoms of hyperthyroidism and reduce thyroid activity by inhibiting the synthesis and release of thyroid hormones.
The preparation of 1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA is usually achieved by the reaction of 4-chloroaniline and phenyl isothiocyanate. First, 4-chloroaniline is reacted with cadmium trichloride to give the 4-chlorophenyl cadmium compound. It is then reacted with phenyl isothiocyanate to give the desired product.
For safety information, health and safety specific guidance, refer to the relevant product safety data sheet (MSDS) before using and handling this compound. This compound may cause irritation to the skin, eyes and respiratory system. Appropriate protective measures should be taken, such as wearing protective glasses and gloves, and handling in a well-ventilated area. At the same time, if contact or inhalation occurs, immediately wash or seek medical help.
One of the main uses of this compound is as an antithyroid agent. It can suppress the symptoms of hyperthyroidism and reduce thyroid activity by inhibiting the synthesis and release of thyroid hormones.
The preparation of 1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA is usually achieved by the reaction of 4-chloroaniline and phenyl isothiocyanate. First, 4-chloroaniline is reacted with cadmium trichloride to give the 4-chlorophenyl cadmium compound. It is then reacted with phenyl isothiocyanate to give the desired product.
For safety information, health and safety specific guidance, refer to the relevant product safety data sheet (MSDS) before using and handling this compound. This compound may cause irritation to the skin, eyes and respiratory system. Appropriate protective measures should be taken, such as wearing protective glasses and gloves, and handling in a well-ventilated area. At the same time, if contact or inhalation occurs, immediately wash or seek medical help.
Last Update：2024-04-09 20:02:46
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