1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone - Names and Identifiers
1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone - Introduction
1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone is an organic compound with the chemical formula C13H10N2O5S.
Nature:
1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone is a white crystalline solid, soluble in water and some organic solvents. It is acidic, forms a sulfonate, and has a pKa of 2.17. It can be decomposed under alkaline conditions to generate the corresponding acid.
Use:
1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone is an important organic synthesis intermediate and fluorescent dye. In chemical synthesis, it is often used in the preparation of pyrazoline fluorescent dyes, metal complexing agents and dye precursors. In addition, it can be used as an indicator in biochemical detection and analysis.
Method:
The method of preparing 1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone can be used to obtain acetylphenol through the esterification reaction of phenol and oxalic acid under the action of a catalyst, after chlorination and pyrazolone cyclization reaction, the target product is obtained. Specific synthetic methods and conditions can refer to the relevant organic synthesis literature.
Safety Information:
The general toxicity of 1-(4-sulfonate)phenyl-3-carboxy-5-pyrazolone is low, but as an organic compound, it is still necessary to comply with the safe operation procedures of chemical laboratories. Keep away from fire and high temperature, avoid contact with skin and eyes, and wear appropriate protective gloves and goggles. In the use of the process need to do a good job of ventilation and avoid inhalation of dust. In the case of accidental contact or ingestion, seek medical advice immediately and show the safety data sheet of the product.
Last Update：2024-04-10 22:29:15