1-(5-Fluoropyridin-2-yl)ethanamine

1-(5-Fluoropyridin-2-yl)ethanamine - Names and Identifiers

Name	1-(5-Fluoropyridin-2-yl)ethanamine
Synonyms	1-(5-Fluoropyridin-2-yl) 2-Cyclopropylideneethanol 2-cyclopropylidene-Ethanol 1-(5-fluoropyridin-2-yl)e... 1-(5-Fluoro-2-pyridyl)ethanamine 1-(5-Fluoropyridin-2-yl)ethanamine 1-(5 -fluoropyridin-2-yl)ethanamine 1-(5-fluoropyridin-2-yl)ethan-1-amine 1-(5-FLUOROPYRIDIN-2-YL)ETHANAMINE-HCL 5-Fluoro-α-Methyl-2-pyridineMethanaMine 5-fluoro-a-methyl-2-Pyridinemethanamine 2-Pyridinemethanamine, 5-fluoro-α-methyl-
CAS	915720-57-9

1-(5-Fluoropyridin-2-yl)ethanamine - Physico-chemical Properties

Molecular Formula	C7H9FN2
Molar Mass	140.16
Storage Condition	2-8°C(protect from light)

1-(5-Fluoropyridin-2-yl)ethanamine - Introduction

1-(5-Fluoropyridin-2-yl)ethanamine is an organic compound with the chemical formula C7H9FN and a molecular weight of 127.15g/mol. It is a colorless to yellow liquid, volatile at room temperature.

Its properties are as follows:
1. Melting point:-58°C
2. Boiling point: 105-107°C
3. Density: 1.094 g/mL
4. Refractive index: 1.531
5. solubility: can be dissolved in water and common organic solvents.

1-(5-Fluoropyridin-2-yl)ethanamine is mainly used in organic synthesis as an intermediate and raw material. It can participate in various chemical reactions, such as substitution reactions, condensation reactions, etc. Because it contains amino and aromatic rings, it can be used to synthesize drugs, pesticides, dyes and other organic compounds.

There are various ways of preparing 1-(5-Fluoropyridin-2-yl)ethanamine. One common method is to react 5-fluoropyridine with ethylamine. First, under appropriate reaction conditions, 5-fluoropyridine reacts with cuprous cyanide (CuCN) to produce a cyano compound. The cyano compound is then reacted with ethylamine under basic conditions to form 1-(5-Fluoropyridin-2-yl)ethanamine.

From a safety point of view, 1-(5-Fluoropyridin-2-yl)ethanamine should be regarded as toxic and irritant. Wear protective gloves, glasses and protective clothing during handling and use. Direct contact with skin, eyes and respiratory tract should be avoided, and good ventilation should be maintained. In case of accidental contact, rinse immediately with water and seek medical help. In addition, it should be properly preserved and handled to avoid mixing with oxidants, strong acids, strong alkalis and other substances to avoid dangerous accidents.

Last Update：2024-04-09 21:01:54