1-(5-Nitro-1H-indazol-1-yl)ethan-1-one

1-(5-Nitro-1H-indazol-1-yl)ethan-1-one - Names and Identifiers

Name	1-Acetyl-5-Nitroindazole
Synonyms	1-Acetyl-5-Nitroindazole 1-ACETYL-5-NITROINDAZOLE 1-Acetyl-5-nitro-1H-indazole 1-(5-nitro-1-indazolyl)ethanone 1-(5-Nitro-indazol-1-yl)-ethanone 1-(5-Nitro-1H-indazol-1-yl)ethanone 1-(5-Nitro-1H-indazol-1-yl)ethan-1-one Ethanone, 1-(5-nitro-1H-indazol-1-yl)-
CAS	13436-55-0
InChI	InChI=1/C9H7N3O3/c1-6(13)11-9-3-2-8(12(14)15)4-7(9)5-10-11/h2-5H,1H3

1-(5-Nitro-1H-indazol-1-yl)ethan-1-one - Physico-chemical Properties

Molecular Formula	C9H7N3O3
Molar Mass	205.17
Density	1.48±0.1 g/cm3(Predicted)
Boling Point	403.7±37.0 °C(Predicted)
Flash Point	197.966°C
Vapor Presure	0mmHg at 25°C
pKa	-3.85±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.683

1-(5-Nitro-1H-indazol-1-yl)ethan-1-one - Risk and Safety

Hazard Symbols

Xi - Irritant

1-(5-Nitro-1H-indazol-1-yl)ethan-1-one - Introduction

1-acetyl-5-nitroindazole is an organic compound with the chemical formula C10H8N4O3. The following is a description of its nature, use, formulation and safety information:

Nature:
1-acetyl -5-nitroindazole is a yellow crystal, soluble in acid, alcohol and organic solvents, insoluble in water. It has a certain degree of stability and is relatively stable at room temperature, but external stimuli such as heat, friction and impact can cause an explosion.

Use:
1-Acetyl -5-nitroindazole is commonly used as a synthetic intermediate for high-energy chemicals. Its explosive properties make it particularly suitable for the preparation of explosives and propellants, such as common rocket engine propellants.

Preparation Method:
The synthesis of 1-acetyl-5-nitroindazole is usually carried out by the following steps: First, pyridine and nitric acid are mixed in an organic solvent, and then a nitrating agent is added to the mixture, stirred, and cooled to 0°C or less. Next, the 2,4-dinitroindazole after removal of the alkaline substance was dissolved in anhydrous dimethylformamide. Finally, the aluminum oxide solution is slowly added dropwise, and the reaction temperature is 0-5°C. The final product, 1-acetyl -5-nitroindazole, is formed.

Safety Information:
1-acetyl -5-nitroindazole is a toxic substance with explosive properties. During use, storage and transportation, the relevant safety operation regulations shall be strictly observed to prevent contact with fire source, heat source and electric spark. At the same time, it should avoid mixing with strong oxidants, alkaline substances and flammable substances. Appropriate protective equipment such as gloves, goggles and protective clothing must be worn when handling the substance. Operation under inappropriate conditions or incorrect use of the substance may cause explosion, fire and personal injury. Therefore, for non-professionals, contact or handling of the compound should be avoided.

Last Update：2024-04-10 22:29:15