1-(6-Amino-3-pyridinyl)-ethanone - Names and Identifiers
1-(6-Amino-3-pyridinyl)-ethanone - Physico-chemical Properties
Molecular Formula | C7H8N2O
|
Molar Mass | 136.15 |
Density | 1.168 |
Boling Point | 332℃ |
Flash Point | 155℃ |
Vapor Presure | 0mmHg at 25°C |
pKa | 4.76±0.13(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.577 |
1-(6-Amino-3-pyridinyl)-ethanone - Introduction
1-(6-aminopyridin-3-yl)ethanone is an organic compound with the chemical formula C8H10N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
1-(6-aminopyridin-3-yl)ethanone is a solid with a white to light yellow crystalline morphology. It is insoluble in water at normal temperature, but soluble in organic solvents such as ethanol and chloroform. It has a neutral nature and is stable under both acidic and alkaline conditions.
Use:
1-(6-aminopyridin-3-yl)ethanone is widely used in the chemical and pharmaceutical industries. It is an important intermediate compound that can be used in the synthesis of a variety of organic compounds. For example, it can be used in the synthesis of pyridine compounds, fluorescent dyes and pesticides.
Method:
The preparation method of 1-(6-aminopyridin-3-yl)ethanone can be achieved by the reaction of p-acetylchloroacetate and pyridine. The specific step is to react acetyl chloroacetate and pyridine under alkaline or acidic conditions, and then purify the target product by crystallization or distillation.
Safety Information:
When using 1-(6-aminopyridin-3-yl)ethanone, you need to pay attention to the following safety precautions:
-It is an organic compound with certain toxicity, so you should follow safe operating procedures when using it, avoid contact with skin and eyes, and avoid inhaling its gas or dust.
-During storage and handling, it should be stored in a sealed container, away from fire and oxidizing agents.
-Dispose of waste in an appropriate manner in accordance with local regulations and rules.
Last Update:2024-04-10 22:29:15