1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE - Names and Identifiers
1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE - Physico-chemical Properties
Molecular Formula | C7H7NO4
|
Molar Mass | 169.13 |
Density | 1.4523 (rough estimate) |
Melting Point | 69 °C |
Boling Point | 298.4°C (rough estimate) |
Flash Point | 105.8°C |
Solubility | soluble in Toluene |
Vapor Presure | 0.0206mmHg at 25°C |
Appearance | Crystals and Chunks |
Color | Yellow |
Storage Condition | 2-8°C |
Refractive Index | 1.5500 (estimate) |
1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R40 - Limited evidence of a carcinogenic effect
R48/20/22 -
R36 - Irritating to the eyes
R22 - Harmful if swallowed
|
Safety Description | S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
WGK Germany | 2 |
HS Code | 29251900 |
1-(ACRYLOYLOXY)-2,5-PYRROLIDINEDIONE - Introduction
Acrylic acid N-hydroxysuccinimide ester(Acrylic acid N-hydroxysuccinimide ester), also referred to as ANH, is a chemical reagent. The following is a description of its nature, use, preparation and safety information.
Nature:
Acrylic acid N-hydroxysuccinimide ester is a colorless liquid with a pungent odor. It is easy to volatilize and burn at room temperature. It is insoluble in water but miscible with organic solvents such as ethanol and dimethylformamide.
Use:
Acrylic acid N-hydroxysuccinimide ester is widely used in the reaction coupling and activation process in organic synthesis. It is mainly used as a cross-linking agent in the biomedical field, and can also be used for immobilization of ligands and antibodies, protein modification and detection analysis.
Preparation Method:
The preparation of Acrylic acid N-hydroxysuccinimide ester is generally obtained by reacting succinimide with acrylic anhydride. This process is generally carried out under an inert atmosphere and purification is achieved by extraction with an organic solvent or by crystallization.
Safety Information:
Acrylic acid N-hydroxysuccinimide ester is irritating and avoid direct contact with skin and eyes. During operation, good ventilation measures should be taken, and acid mist masks and chemical protective glasses should be worn at the same time. In the process of storage and handling, pay attention to prevent leakage or fire. After use, the remaining items should be properly disposed of to avoid environmental pollution.
Last Update:2024-04-09 02:00:46