1-(Cyclohexylcarbonyl)piperazine - Names and Identifiers
1-(Cyclohexylcarbonyl)piperazine - Physico-chemical Properties
Molecular Formula | C11H20N2O
|
Molar Mass | 196.29 |
Density | 1.047±0.06 g/cm3(Predicted) |
Melting Point | 84-89 °C (lit.) |
Boling Point | 350.5±35.0 °C(Predicted) |
Solubility | soluble in Methanol |
Appearance | Solid |
Color | White to brown |
pKa | 8.47±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
1-(Cyclohexylcarbonyl)piperazine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
WGK Germany | 3 |
1-(Cyclohexylcarbonyl)piperazine - Introduction
1-(Cyclohexylcarbonyl)piperazine is an organic compound with the chemical formula C12H20N2O. The following is a description of the nature, use, preparation and safety information of 1-(Cyclohexylcarbonyl)piperazine:
Nature:
1-(Cyclohexylcarbonyl)piperazine is a solid, usually white crystalline powder with a special chemical structure. It is hygroscopic and soluble in many organic solvents, such as ethanol and dimethylformamide.
Use:
1-(Cyclohexylcarbonyl)piperazine has certain applications in the field of medicine and chemical industry. It is often used as a pharmaceutical intermediate for the synthesis of a variety of drugs, such as antipsychotics and pain medications. In addition, it can also be used as an amino hydroxylation reagent in organic synthesis and participate in a variety of organic reactions.
Preparation Method:
1-(Cyclohexylcarbonyl)piperazine can be prepared by reacting a carboxylic acid with piperazine. In the specific preparation process, it is first necessary to heat the carboxylic acid and piperazine in an appropriate solvent, usually using an acid catalyst. After completion of the reaction, the pure product can be obtained by crystallization and filtration.
Safety Information:
1-(Cyclohexylcarbonyl)piperazine are generally relatively safe compounds under normal conditions of use. However, like all chemicals, it also needs to follow appropriate safe handling methods. Wear protective gloves, glasses and masks to avoid contact with skin and eyes. When handling this substance, it needs to be carried out in a well-ventilated environment and no dust should be inhaled. If ingested or inhaled, please seek medical treatment in time.
Last Update:2024-04-09 20:52:54