1-(phenylmethyl)-2-Azetidinemethanamine - Names and Identifiers
1-(phenylmethyl)-2-Azetidinemethanamine - Physico-chemical Properties
Molecular Formula | C11H16N2
|
Molar Mass | 176.26 |
Density | 1.068g/cm3 |
Boling Point | 264.816°C at 760 mmHg |
Flash Point | 103.903°C |
Vapor Presure | 0.009mmHg at 25°C |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.578 |
1-(phenylmethyl)-2-Azetidinemethanamine - Introduction
It is an organic compound with the chemical formula C12H16N2. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: Colorless to light yellow liquid or solid.
-Molecular weight: 188.27g/mol.
-Melting point: 55-57°C.
-Boiling point: 265-267°C.
-Density: 1.040g/cm³.
-Solubility: Soluble in most organic solvents.
Use:
-is an organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used to synthesize various drugs, pesticides and chemical reagents.
Preparation Method:
-there are many preparation methods, the following is a common method:
1.1-butyl -2-bromoacetic acid methyl ester and debenzylation agent (such as aluminum chloride) are reacted in an appropriate solvent to obtain 1-butyl -2-azetidine carboxylic acid methyl ester.
2. react 1-butyl -2-azetidine methyl formate with benzylamine, and make it undergo nucleophilic substitution reaction at the amine position under acidic conditions to generate benzylamine.
Safety Information:
-must be operated in a well-ventilated place.
-It is an irritant substance that may cause irritation and inflammation after contact with the skin and eyes.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing.
-avoid inhalation of its vapor or dust, please pay attention to protective measures when using.
-When using, storing and handling, please refer to the safety technical instructions for chemicals.
Last Update:2024-04-09 15:17:57