1-(pyridin-2-ylmethyl)piperazinediium

1-(pyridin-2-ylmethyl)piperazinediium - Names and Identifiers

Name	1-(Pyridin-2-ylmethyl)piperazine
Synonyms	AKOS B004020 BUTTPARK 368-66 CHEMBRDG-BB 4101647 ART-CHEM-BB B004020 (2-PYRIDYLMETHYL)PIPERAZINE 1-[(2-PYRIDYL)METHYL]PIPERAZINE 1-PYRIDIN-2-YLMETHYL-PIPERAZINE 1-Pyridin-2-Ylmethyl-Piperazine 1-(2-pyridinylmethyl)-Piperazine 1-(Pyridin-2-ylmethyl)piperazine Piperazine, 1-(2-pyridinylmethyl)- 1-(pyridin-2-ylmethyl)piperazinediium 1-PYRIDIN-2-YLMETHYL-PIPERAZINE DIHYDROCHLORIDE
CAS	55579-01-6
InChI	InChI=1/C10H15N3/c1-2-4-12-10(3-1)9-13-7-5-11-6-8-13/h1-4,11H,5-9H2/p+2

1-(pyridin-2-ylmethyl)piperazinediium - Physico-chemical Properties

Molecular Formula	C10H15N3
Molar Mass	177.25
Density	1.073±0.06 g/cm3(Predicted)
Boling Point	91-93°C 0,4mm
Flash Point	124.1°C
Vapor Presure	0.00355mmHg at 25°C
pKa	9.00±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

1-(pyridin-2-ylmethyl)piperazinediium - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class	IRRITANT

1-(pyridin-2-ylmethyl)piperazinediium - Introduction

1-(Pyridin-2-ylmethyl)piperazine is an organic compound with the chemical formula C12H16N2. It is a white crystalline solid that is stable at room temperature. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-(Pyridin-2-ylmethyl)piperazine has a structure with pyridine and piperazine groups, so it has two different environments. It has a molecular weight of 196.27g/mol, a boiling point of 289°C (decomposition) and a melting point of 91-93°C. It has low solubility in water, but better solubility in organic solvents.

Use:
1-(Pyridin-2-ylmethyl)piperazine are often used as intermediates or ligands in organic synthesis, such as complex catalysts, synthesis of coordination compounds, etc. In addition, it can also be used as a raw material for certain drugs in the pharmaceutical field (such as antidepressants).

Preparation Method:
There are many methods for preparing 1-(Pyridin-2-ylmethyl)piperazine, and the following two are common:
1. Pyridine reacts with piperazine to generate 1-(pyridin-2-yl) methylpiperazine, which is then subjected to N-methylation reaction to obtain the target product.
2. The cyano group is introduced into piperazine, and then hydrogenation reaction is carried out to obtain 1-(Pyridin-2-ylmethyl)piperazine.

Safety Information:
1-(Pyridin-2-ylmethyl)piperazine is relatively safe under general operating conditions. However, as with any chemical substance, it needs to be used with caution and in accordance with safe operating guidelines. Contact with skin, eyes and respiratory tract should be avoided during handling and storage. Store properly and away from ignition and oxidizing agents.

Last Update：2024-04-09 20:49:11