1-(pyrimidin-2-yl)ethanone
1-(pyrimidin-2-yl)ethanone
CAS: 53342-27-1
Molecular Formula: C6H6N2O
1-(pyrimidin-2-yl)ethanone - Names and Identifiers
1-(pyrimidin-2-yl)ethanone - Physico-chemical Properties
| Molecular Formula | C6H6N2O |
| Molar Mass | 122.12 |
| Density | 1.136 |
| Melting Point | 52℃ |
| Boling Point | 254℃ |
| Flash Point | 111℃ |
| Vapor Presure | 0.017mmHg at 25°C |
| pKa | -1.05±0.13(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.516 |
1-(pyrimidin-2-yl)ethanone - Introduction
1-(pyrimidin-2-yl)ethanone, chemical formula C7H7NO, is an organic compound. The following is a brief description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1-(pyrimidin-2-yl)ethanone is a white to light yellow crystalline powder.
-Solubility: It dissolves in some organic solvents (such as ethanol, dimethylformamide).
Use:
-Chemical synthesis: 1-(pyrimidin-2-yl)ethanone can be used as chemical synthesis intermediates and play an important role in organic chemical reactions.
-Drug: It is also used in drug research and preparation, for example, as a synthetic intermediate for antiviral, anti-tuberculosis, and anti-cancer drugs.
Preparation Method:
- 1-(pyrimidin-2-yl)ethanone is prepared in a variety of ways, commonly used methods include:
a. is obtained by reacting 2-chloroacetyl chloride with pyrimidine.
B. it is obtained by the reflux reaction of 2-hydroxyacetic acid and pyrimidine in anhydrous ethanol.
Safety Information:
- 1-(pyrimidin-2-yl)ethanone need to be handled and stored in accordance with the safe operation specifications of general organic compounds.
-It may be irritating to the eyes and skin, and direct contact should be avoided.
-Appropriate laboratory safety measures, such as wearing protective glasses, laboratory clothing and gloves, are required for use and handling. At the same time, make sure to operate in a well-ventilated environment and avoid inhaling dust or gas.
-In case of discomfort or maladjustment after contact or inhalation, medical help should be sought promptly.
Nature:
-Appearance: 1-(pyrimidin-2-yl)ethanone is a white to light yellow crystalline powder.
-Solubility: It dissolves in some organic solvents (such as ethanol, dimethylformamide).
Use:
-Chemical synthesis: 1-(pyrimidin-2-yl)ethanone can be used as chemical synthesis intermediates and play an important role in organic chemical reactions.
-Drug: It is also used in drug research and preparation, for example, as a synthetic intermediate for antiviral, anti-tuberculosis, and anti-cancer drugs.
Preparation Method:
- 1-(pyrimidin-2-yl)ethanone is prepared in a variety of ways, commonly used methods include:
a. is obtained by reacting 2-chloroacetyl chloride with pyrimidine.
B. it is obtained by the reflux reaction of 2-hydroxyacetic acid and pyrimidine in anhydrous ethanol.
Safety Information:
- 1-(pyrimidin-2-yl)ethanone need to be handled and stored in accordance with the safe operation specifications of general organic compounds.
-It may be irritating to the eyes and skin, and direct contact should be avoided.
-Appropriate laboratory safety measures, such as wearing protective glasses, laboratory clothing and gloves, are required for use and handling. At the same time, make sure to operate in a well-ventilated environment and avoid inhaling dust or gas.
-In case of discomfort or maladjustment after contact or inhalation, medical help should be sought promptly.
Last Update：2024-04-09 21:11:58
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Product Name: Ethanone,1-(2-pyrimidinyl)- Visit Supplier Webpage Request for quotation
CAS: 53342-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 53342-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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