1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine

1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine - Names and Identifiers

Name	1-Boc-3-Methylaminopyrrolidine
Synonyms	1-Boc-3-Methylaminopyrrolidine 1-BOC-3-METHYLAMINOPYRROLIDINE 1-(tert-Butyloxycarbonyl)-3-methylaminopyrro 3-Methylamino-1-tert-butoxycarbonylpyrrolidine 1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine tert-butyl 3-(methylamino)pyrrolidine-1-carboxylate 3-Methylaminopyrrolidine-1-carboxylic acid tert-butyl ester 3-METHYLAMINO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester(9CI)
CAS	454712-26-6
InChI	InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-6-5-8(7-12)11-4/h8,11H,5-7H2,1-4H3

1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine - Physico-chemical Properties

Molecular Formula	C10H20N2O2
Molar Mass	200.28
Density	1.03
Boling Point	269 °C
Flash Point	117 °C
Vapor Presure	0.00725mmHg at 25°C
pKa	10.02±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.485

1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R50 - Very Toxic to aquatic organisms
Safety Description	S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN2811
HS Code	29339900

1-(tert-Butyloxycarbonyl)-3-methylaminopyrrolidine - Introduction

It is an organic compound with a chemical formula of C10H19NO2 and a molecular weight of 185.26g/mol. It is a colorless liquid with a strong ammonia odor.

One of the main uses of calcium is as a protecting group in organic synthesis. Among them, Boc is the abbreviation of butoxycarbonyl, which can protect the reactivity of amine groups. In addition, it can also be used in the synthesis of drugs, reagents and dyes and other compounds.
The preparation method of
is usually carried out by the following steps: First, 3-methylaminopyrrolidine is reacted with tetramethylchloroformate to obtain a tetramethylformate derivative. Subsequently, deprotection by alkali treatment gives the final product.

Regarding safety information, may be irritating to eyes, skin and respiratory tract, must wear appropriate protective measures. During the operation, attention should be paid to avoid inhalation, contact with skin and eyes, and wash in time when there is discomfort. At the same time, it should be used in a well-ventilated place and stored in a cool and dry place, away from fire and oxidants. Please read the relevant safety data sheet of the product carefully before use.

Last Update：2024-04-09 21:11:58