1-(tert-butoxycarbonyl)-4-methylidene-L-proline
N-Boc-4-methylene-L-proline
CAS: 84348-38-9
Molecular Formula: C11H17NO4
1-(tert-butoxycarbonyl)-4-methylidene-L-proline - Names and Identifiers
1-(tert-butoxycarbonyl)-4-methylidene-L-proline - Physico-chemical Properties
| Molecular Formula | C11H17NO4 |
| Molar Mass | 227.26 |
| Density | 1.18±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 110-115 °C |
| Boling Point | 349.9±42.0 °C(Predicted) |
| Flash Point | 165.389°C |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 3.80±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.513 |
| MDL | MFCD01861787 |
1-(tert-butoxycarbonyl)-4-methylidene-L-proline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
1-(tert-butoxycarbonyl)-4-methylidene-L-proline - Introduction
N-Boc-4-methylene-L-proline is an organic compound whose structure contains a N-Boc protecting group and a methylene substituent. Its chemical formula is C10H17NO4. The following is a description of its nature, use, preparation and safety information:
1. nature:
N-Boc-4-methylene-L-proline are colorless to pale yellow crystals or powder. It is stable at room temperature, soluble in many organic solvents such as chloroform and dichloromethane, slightly soluble in ethanol.
2. use:
N-Boc-4-methylene-L-proline are commonly used in the field of organic synthesis. It can be used as an intermediate in the preparation of antitumor drugs, antiviral drugs and antibacterial drugs. In addition, it is also a common catalyst and ligand.
3. preparation method:
The preparation of N-Boc-4-methylene-L-proline usually adopts chemical synthesis. A common method is by reacting p-methylproline with a Boc-carbamate to give the desired product under appropriate conditions.
4. Safety Information:
N-Boc-4-methylene-L-proline safety information is limited. It may be irritating to the eyes, skin and respiratory system, so it is recommended to wear appropriate protective equipment during handling. At the same time, it should be stored in a dark, dry and ventilated place. For safe operation and storage, please refer to the relevant safety data form or consult the supplier. When using, it is recommended to follow the correct laboratory procedures.
1. nature:
N-Boc-4-methylene-L-proline are colorless to pale yellow crystals or powder. It is stable at room temperature, soluble in many organic solvents such as chloroform and dichloromethane, slightly soluble in ethanol.
2. use:
N-Boc-4-methylene-L-proline are commonly used in the field of organic synthesis. It can be used as an intermediate in the preparation of antitumor drugs, antiviral drugs and antibacterial drugs. In addition, it is also a common catalyst and ligand.
3. preparation method:
The preparation of N-Boc-4-methylene-L-proline usually adopts chemical synthesis. A common method is by reacting p-methylproline with a Boc-carbamate to give the desired product under appropriate conditions.
4. Safety Information:
N-Boc-4-methylene-L-proline safety information is limited. It may be irritating to the eyes, skin and respiratory system, so it is recommended to wear appropriate protective equipment during handling. At the same time, it should be stored in a dark, dry and ventilated place. For safe operation and storage, please refer to the relevant safety data form or consult the supplier. When using, it is recommended to follow the correct laboratory procedures.
Last Update：2024-04-09 21:11:58
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Product Name: N-Boc-4-Methylene-L-Proline Visit Supplier Webpage Request for quotation
CAS: 84348-38-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 84348-38-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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