1-(trimethylsilyl)-1-Pentyn-3-one
1-(trimethylsilyl)-1-Pentyn-3-one
CAS: 18387-58-1
Molecular Formula: C8H14OSi
1-(trimethylsilyl)-1-Pentyn-3-one - Names and Identifiers
| Name | 1-(trimethylsilyl)-1-Pentyn-3-one |
| Synonyms | 1-(Trimethylsilyl)-1-pentyn-3-one 1-(trimethylsilyl)-1-Pentyn-3-one 1-Pentyn-3-one, 1-(trimethylsilyl)- |
| CAS | 18387-58-1 |
1-(trimethylsilyl)-1-Pentyn-3-one - Physico-chemical Properties
| Molecular Formula | C8H14OSi |
| Molar Mass | 154.28 |
1-(trimethylsilyl)-1-Pentyn-3-one - Introduction
1-(trimethylsilyl)-1-Pentyn-3-one is an organic compound with the chemical formula C10H18OSi. The following is a description of its nature, use, preparation and safety information:
Nature:
1-(trimethylsilyl)-1-Pentyn-3-one is a colorless to light yellow liquid. It has a relatively low boiling and melting point and is soluble in many common organic solvents such as ethanol, acetone and dichloromethane.
Use:
1-(trimethylsilyl)-1-Pentyn-3-one is often used as an important reagent in organic synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc. In addition, it can also be used as a solvent, catalyst and reaction intermediate in organic synthesis reactions.
Method:
The preparation of 1-(trimethylsilyl)-1-Pentyn-3-one can be completed by the following steps:
1. First, a solution of trimethylmagnesium silicide (Me3SiMgBr) reacts with acetone to generate Me3Si-CH = C(OMgBr)-C(= O)-ch3.
2. Next, the reaction product is acidified with a certain amount of acetic acid to obtain the target product 1-(trimethylsilyl)-1-Pentyn-3-one.
Safety Information:
1-(trimethylsilyl)-1-Pentyn-3-one is not particularly hazardous under regular conditions. However, it should still be handled carefully in the chemical laboratory and strictly follow the relevant safe operating procedures. When using, avoid direct contact with skin and eyes, and ensure good ventilation conditions. Also, use personal protective equipment such as lab gloves and safety glasses.
Nature:
1-(trimethylsilyl)-1-Pentyn-3-one is a colorless to light yellow liquid. It has a relatively low boiling and melting point and is soluble in many common organic solvents such as ethanol, acetone and dichloromethane.
Use:
1-(trimethylsilyl)-1-Pentyn-3-one is often used as an important reagent in organic synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc. In addition, it can also be used as a solvent, catalyst and reaction intermediate in organic synthesis reactions.
Method:
The preparation of 1-(trimethylsilyl)-1-Pentyn-3-one can be completed by the following steps:
1. First, a solution of trimethylmagnesium silicide (Me3SiMgBr) reacts with acetone to generate Me3Si-CH = C(OMgBr)-C(= O)-ch3.
2. Next, the reaction product is acidified with a certain amount of acetic acid to obtain the target product 1-(trimethylsilyl)-1-Pentyn-3-one.
Safety Information:
1-(trimethylsilyl)-1-Pentyn-3-one is not particularly hazardous under regular conditions. However, it should still be handled carefully in the chemical laboratory and strictly follow the relevant safe operating procedures. When using, avoid direct contact with skin and eyes, and ensure good ventilation conditions. Also, use personal protective equipment such as lab gloves and safety glasses.
Last Update：2024-04-09 21:11:58
