1-Acetyl-2-isonicotinoylhydrazine-d4 - Names and Identifiers
1-Acetyl-2-isonicotinoylhydrazine-d4 - Physico-chemical Properties
Molecular Formula | C8H9N3O2
|
Molar Mass | 179.17596 |
Melting Point | 161-163°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | -20°C Freezer |
1-Acetyl-2-isonicotinoylhydrazine-d4 - Introduction
Isoniazid-d4 (Acetyl Isoniazid-d4) is a commonly used labeled compound in the field of drug research. The following is a description of the properties, uses, preparation and safety information of the compound:
1. Nature:
-Molecular formula: C7H3D4N2O2
-Molecular weight: 150.18g/mol
-Appearance: Colorless solid
-Melting point: 170-172 ° C
-Storage conditions: Keep away from light at room temperature
2. Use:
Acetyl Isoniazid-d4 is widely used in pharmacokinetics and drug metabolism research. It is often used as a tracer marker for drug metabolism pathways to study the metabolic processes of drugs in the body and their interactions with drug-metabolizing enzymes.
3. Preparation method:
A commonly used preparation method is to react Acetyl Isoniazid (Acetyl Isoniazid) with a deuterated reagent through chemical synthesis to obtain Acetyl Isoniazid-d4. The specific steps can be synthesized according to the existing methods in the laboratory.
4. Safety Information:
- Acetyl Isoniazid-d4 is a chemical and should be handled in accordance with laboratory safety procedures.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, to avoid contact with skin, eyes and esophagus.
-Avoid inhaling powders or vapors of the compound. Laboratory operations should be carried out in a well-ventilated area.
-Please store the compound properly and avoid contact with oxidants, strong acids, strong bases and other substances to prevent fire or other dangerous accidents.
Last Update:2024-04-09 02:00:54