1-Acetyl-2-phenylethyne
4-phenyl-3-butyn-2-one
CAS: 1817-57-8
Molecular Formula: C10H8O
1-Acetyl-2-phenylethyne - Names and Identifiers
| Name | 4-phenyl-3-butyn-2-one |
| Synonyms | Phenylbutynone 4-phenyl-3-butyn-2-on 4-phenylbut-3-yn-2-one 4-phenyl-3-butyn-2-0ne 4-PHENYL-3-BUTYN-2-ONE 4-Phenyl-3-Batyu-2-One 4-Phenyl-3-batyu-2-one 4-phenyl-3-butyn-2-one 1-Phenyl-1-butyn-3-one 1-Acetyl-2-phenylethyne 3-Butyn-2-one, 4-phenyl- |
| CAS | 1817-57-8 |
| EINECS | 217-327-1 |
| InChI | InChI=1/C10H8O/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6H,1H3 |
1-Acetyl-2-phenylethyne - Physico-chemical Properties
| Molecular Formula | C10H8O |
| Molar Mass | 144.17 |
| Density | 0.99 g/mL at 25 °C (lit.) |
| Melting Point | 4°C |
| Boling Point | 75-76 °C/0.8 mmHg (lit.) |
| Flash Point | 203°F |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 0.019mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.02 |
| Color | Colorless to Yellow to Green |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.574(lit.) |
| MDL | MFCD00008776 |
1-Acetyl-2-phenylethyne - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | UN 3334 |
| WGK Germany | 3 |
| RTECS | ES0890000 |
1-Acetyl-2-phenylethyne - Introduction
4-phenyl-3-butyn-2-one is an organic compound with the chemical formula C14H10O. The following is a description of its nature, use, preparation and safety information:
Nature:
4-phenyl-3-butyn-2-one is a solid compound having the appearance of white crystals. It has a melting point of 84-85°C and a boiling point of 355°C. It is soluble in organic solvents such as ethers and alcohols at normal temperature.
Use:
4-phenyl-3-butyn-2-one is commonly used as an intermediate in chemical synthesis. It has some important applications in the field of medicine. For example, it can be used in the synthesis of certain drugs, such as anti-cancer drugs, anti-viral drugs and anti-inflammatory drugs. In addition, it can also be used as a catalyst in organic synthesis reactions and as a starting material for cyclization reactions.
Method:
4-phenyl-3-butyn-2-one can be prepared in a variety of ways. A common method is the reaction of benzylpropanedione and Phenyl Ketone under alkaline conditions by carboxylic acid or hydrogenation reduction. Other preparation methods include catalytic hydrogenation and the use of specific catalysts.
Safety Information:
The safety of 4-phenyl-3-butyn-2-one is high. It is not easy to burn under normal use conditions, but may produce irritating and toxic smoke at high temperatures. When operating, wear appropriate personal protective equipment, such as goggles, protective gloves and lung protection devices to avoid direct contact and inhalation. In addition, it should be stored in a closed container, away from fire and oxidizing agents. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help. In the use and handling process, please follow the relevant safety procedures.
Nature:
4-phenyl-3-butyn-2-one is a solid compound having the appearance of white crystals. It has a melting point of 84-85°C and a boiling point of 355°C. It is soluble in organic solvents such as ethers and alcohols at normal temperature.
Use:
4-phenyl-3-butyn-2-one is commonly used as an intermediate in chemical synthesis. It has some important applications in the field of medicine. For example, it can be used in the synthesis of certain drugs, such as anti-cancer drugs, anti-viral drugs and anti-inflammatory drugs. In addition, it can also be used as a catalyst in organic synthesis reactions and as a starting material for cyclization reactions.
Method:
4-phenyl-3-butyn-2-one can be prepared in a variety of ways. A common method is the reaction of benzylpropanedione and Phenyl Ketone under alkaline conditions by carboxylic acid or hydrogenation reduction. Other preparation methods include catalytic hydrogenation and the use of specific catalysts.
Safety Information:
The safety of 4-phenyl-3-butyn-2-one is high. It is not easy to burn under normal use conditions, but may produce irritating and toxic smoke at high temperatures. When operating, wear appropriate personal protective equipment, such as goggles, protective gloves and lung protection devices to avoid direct contact and inhalation. In addition, it should be stored in a closed container, away from fire and oxidizing agents. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help. In the use and handling process, please follow the relevant safety procedures.
Last Update：2024-04-09 20:52:54
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CAS: 1817-57-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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