1-Acetyl-2-pyrrolidinecarboxamide

1-Acetyl-2-pyrrolidinecarboxamide - Names and Identifiers

Name	1-acetylprolinamide
Synonyms	1-acetylprolinamide 1-Acetyl-2-pyrrolidinecarboxamide 1-acetylpyrrolidine-2-carboxaMide 2-Pyrrolidinecarboxamide, 1-acetyl- 2-Pyrrolidinecarboxamide,1-acetyl-(6CI,9CI)
CAS	30130-35-9
InChI	InChI=1/C7H12N2O2/c1-5(10)9-4-2-3-6(9)7(8)11/h6H,2-4H2,1H3,(H2,8,11)

1-Acetyl-2-pyrrolidinecarboxamide - Physico-chemical Properties

Molecular Formula	C7H12N2O2
Molar Mass	156.18
Density	1.206g/cm³
Boling Point	411.9°C at 760 mmHg
Flash Point	202.9°C
Vapor Presure	5.38E-07mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.519

1-Acetyl-2-pyrrolidinecarboxamide - Introduction

1-acetylprolinamide is an organic compound with the chemical formula C7H10N2O2.

Its properties mainly include:
-Appearance: Colorless to light yellow crystalline solid.
-Melting point: 132-133 ° C.
-Solubility: better solubility in water, alcohols and ethers.

The main uses of 1-acetylprolinamide are:
-Biochemical research: used as a catalyst, intermediate or reagent in chemical synthesis and biological reactions.
-Pharmacy: As an intermediate in the synthesis of drugs, it is used to synthesize compounds with biological activity.

The method of preparing 1-acetylprolinamide is usually carried out by the following steps:
1.2-pyrrolidine carboxylic acid is reacted with anhydride to generate 2-pyrrolidine acid chloride.
2. React 2-pyrrolidine chloride with acetyl chloride to generate 1-acetyl -2-pyrrolidine chloride.
3. React 1-acetyl -2-pyrrolidine chloride with ammonia to generate 1-acetylprolinamide.

Regarding safety information, 1-acetylprolinamide has not been extensively studied for toxicity and harmfulness. During use or handling, laboratory safety practices should be observed, such as wearing appropriate personal protective equipment (such as gloves, glasses and laboratory coats), and avoiding inhalation, ingestion or contact with skin. It is recommended to use the compound under the guidance of a professional.

Last Update：2024-04-09 20:02:46