1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE(WX665160) - Names and Identifiers
Name | 1-Piperidinecarboxylicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester
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Synonyms | 1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE N-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE 1-N-Boc-2-(methoxymethylcarbamoyl)piperidine 1-Boc-2-(N-Methoxy-N-MethylcarbaMoyl)piperidine 1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE(WX665160) tert-butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 1-[tert-Butyloxycarbonyl]-2-[N-methoxy-N-methylcarbamoyl]piperidine 1-[Tert-Butyloxycarbonyl]-2-[N-methoxy-N-methylcarbamoyl]piperidine 1,1-Dimethylethyl2-(N-methoxy-N-methylcarbamoyl)piperidine-1-carboxylate 1-Piperidinecarboxylicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester 1-Piperidinecarboxylic acid, 2-[(MethoxyMethylaMino)carbonyl]-, 1,1-diMethylethyl ester
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CAS | 211310-10-0
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1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE(WX665160) - Physico-chemical Properties
Molecular Formula | C13H24N2O4
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Molar Mass | 272.34 |
Storage Condition | 2-8℃ |
1-BOC-2-(METHOXY-METHYL-CARBAMOYL)PIPERIDINE(WX665160) - Introduction
1-piperidinecarboxyllicacid, 2-[(methoxylamino) carbonyl]-, 1,1-dimethylethyl ester, also known as 1-piperidinecarboxyllicacid, 2-[(methoxylamino) carbonyl]-, 1,1-dimethylethyster, it is a common organic compound. The following is its nature, use, preparation and safety information:
Nature:
1-Piperidinecarboxylicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimenthylethyl ester is a white crystalline solid, stable at ambient temperatures. It is in the form of a solid, but may also be dissolved in an appropriate solvent.
Use:
1-Piperidinecarboxylicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester is a common reagent in organic synthesis and has many uses. It can be used as a protecting group for carbamic acid and is used in the synthesis to protect the amine group from unwanted reactions until the protecting group is removed when needed. In addition, it can also be used for deprotection reactions to remove protected amine groups.
Method:
The synthesis of 1-piperidinecarboxyllicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester is usually carried out by the following steps:
1. Piperazine and a certain concentration of sodium hydroxide or potassium hydroxide condensation reaction, generating the corresponding activation of piperazine ester.
2. The activated piperazine ester is reacted with Boc-carbamate to produce 1-Piperidinecarboxylicacid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyyl ester.
3. Finally, the target product was obtained by purification and crystallization.
Safety Information:
1-Piperidinecarboxylicacid, 2-[(methoxylamino) carbonyl]-, 1,1-dimethylethyl ester is generally safe in regular use, but the following matters should be noted:
-It may be irritating to the skin, eyes and respiratory tract and direct contact should be avoided.
-Appropriate protective measures such as gloves, goggles and respiratory protection are required during use.
-Store and handle the compound to avoid reaction with other chemicals.
-If ingested or inhaled in large quantities, seek medical attention immediately.
Last Update:2024-04-09 21:00:56