1-BOC-2-HYDROXYMETHYL-AZETIDINE

1-BOC-2-HYDROXYMETHYL-AZETIDINE - Names and Identifiers

Name	N-Boc-2-azetidinemethanol
Synonyms	N-Boc-2-azetidinemethanol 1-Boc-2-azetidinemethanol 1-BOC-2-HYDROXYMETHYL-AZETIDINE [1-(TERT-BUTOXYCARBONYL)AZETIDIN-2-YL]METHANOL tert-Butyl 2-(hydroxyMethyl)azetidine-1-carboxylate R,S-1-[(1,1-Dimethylethoxy)carbonyl]azetidine-2-methanol 2-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Azetidinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester
CAS	174346-82-8

1-BOC-2-HYDROXYMETHYL-AZETIDINE - Physico-chemical Properties

Molecular Formula	C9H17NO3
Molar Mass	187.24
Melting Point	132-135
Boling Point	270.349℃ at 760 mmHg
Storage Condition	2-8°C

1-BOC-2-HYDROXYMETHYL-AZETIDINE - Introduction

N-Boc-2-azetidinemethanol is an organic compound whose chemical name is 1-(tert-butyloxycarbonyl)-2-(amino)-2-methylpropyl alcohol.

Nature:
N-Boc-2-azetidinemethanol is a colorless liquid with weak alkalinity. Its molecular formula is C12H23NO3 and its relative molecular mass is 229.32g/mol. The compound has a melting point of -13°C and a boiling point of 185°C.

Use:
N-Boc-2-azetidinemethanol is an important intermediate compound, which is widely used in the field of organic synthesis. It can be used in the preparation of various drugs, bioactive molecules and functional materials, and as a protecting group in the synthesis of peptides or proteins.

Method:
The preparation process of N-Boc-2-azetidinemethanol is relatively simple. A common method is to react azepine with tert-butyl chloroformate. The specific reaction conditions can be optimized according to actual needs.

Safety Information:
The N-Boc-2-azetidinemethanol is relatively stable under general conditions, but it still needs to be operated with caution. It may cause irritation to the eyes, skin and respiratory tract, so direct contact should be avoided during operation. At the same time, it should be operated in a well-ventilated laboratory and take appropriate personal protective measures, such as wearing gloves, goggles and protective clothing. After disposal, waste should be properly disposed of and disposed of in accordance with relevant regulations. In case of inhalation or improper contact, seek medical help immediately.

Last Update：2024-04-09 21:11:58