1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE - Names and Identifiers

Name	1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
Synonyms	1-Boc-5-aMinoindoline 5-AMINO-1-BOC-2,3-DIHYDROINDOLE 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE 1-Boc-2,3-dihydro-1H-indol-5-amine 2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate 5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 1H-Indole-1-carboxylic acid, 5-amino-2,3-dihydro-, 1,1-dimethylethyl ester
CAS	129487-92-9

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE - Physico-chemical Properties

Molecular Formula	C13H18N2O2
Molar Mass	234.29
Density	1.177±0.06 g/cm3(Predicted)
Boling Point	385.2±41.0 °C(Predicted)
pKa	5.44±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE - Risk and Safety

Hazard Class

IRRITANT

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE - Introduction

1-BOC-5-amino-2, 3-indoline is an organic compound with a tert-butyl carbonate protecting group (BOC) and an amino functional group in its molecular structure. The following is a description of its nature, use, formulation and safety information:

Nature:
1-BOC-5-amino-2, 3-indoline is a solid, white crystal or crystalline powder at room temperature. It is soluble in some organic solvents, such as methanol and propylene glycol, while the solubility in water is low. It has thermal stability and chemical stability, and can undergo chemical reactions under certain conditions.

Use:
1-BOC-5-amino -2, 3-indoline is mainly used in the field of organic synthesis. It can be used as an intermediate for the synthesis of other compounds, especially in the synthesis of drugs. It is a common amino protecting group that can protect the amino group during the synthesis to prevent unwanted reactions. When necessary, the protecting group can be removed by appropriate reaction conditions to obtain the desired amino compound.

Preparation Method:
1-BOC-5-amino-2, 3-indoline is generally obtained by chemical synthesis. A common preparation method is by the reaction of 2,3-indoline and tert-butyl bromoacetate to give 1-BOC-5-amino-2, 3-indoline.

Safety Information:
1-BOC-5-amino -2, 3-indoline has certain safety under conventional conditions. However, when handling this compound, care should be taken to follow laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and protective glasses. In addition, it should be stored in a dry, cool, well-ventilated place, away from fire and oxidants. If ingestion or contact with skin or eyes, seek medical attention immediately and obtain professional first aid.

Last Update：2024-04-09 20:52:54