1-BROMO-3-ETHOXY-2-IODOBENZENE - Names and Identifiers
1-BROMO-3-ETHOXY-2-IODOBENZENE - Physico-chemical Properties
Molecular Formula | C8H8BrIO
|
Molar Mass | 326.96 |
Storage Condition | 2-8℃ |
Sensitive | IRRITANT |
MDL | MFCD11504954 |
1-BROMO-3-ETHOXY-2-IODOBENZENE - Introduction
It is an organic compound whose chemical formula is C8H8BrIO. It is a colorless to pale yellow solid, solid form at room temperature.
The following properties are:
1. Solubility: In organic solvents such as ethanol, dichloromethane and ether, the solubility is good, insoluble in water.
2. Melting point: about 50-52°C.
3. Boiling point: about 280-285°C.
4. density: about 2.0 g/cm.
It is often used as an intermediate in organic synthesis. It can participate in Suzuki reaction, Stille reaction, etc., for the construction of C- C and C- heteroatom bonds. In addition, it can also be used as a precursor for other important compounds in organic synthesis.
The preparation method of
is mainly obtained by the reaction of iodobenzene and ethanol in the presence of hydrogen bromide. Specific steps are:
1. Add iodobenzene and ethanol to the reaction flask.
2. Add an appropriate amount of hydrogen bromide as a catalyst, heat the reaction system and stir.
3. After completion of the reaction, the target product was obtained by filtration and washing.
Regarding safety information, is an organic compound, you need to pay attention to the following safety measures when operating:
1. should be operated in a well-ventilated laboratory, avoid inhaling its gas or dust.
2. Use personal protective equipment such as protective gloves, goggles, and lab coats.
3. avoid contact with skin and eyes, if contact, should immediately rinse with plenty of water.
4. storage should avoid contact with oxidants, strong acids and other substances, avoid fire and high temperature.
Last Update:2024-04-10 22:29:15