1-Benzyl-2,3-isopropylidene-sn-glycerol

1-Benzyl-2,3-isopropylidene-sn-glycerol - Names and Identifiers

Name	(R)-4-bebzyloxymethyl-2,2-dimethyl-1,3-dioxolane
Synonyms	1-Benzyl-2,3-isopropylidene-sn-glycerol L-α,β-Isopropylideneglycerol-γ-benzyl ether (R)-4-BENZYLOXYMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE (R)-4-bebzyloxymethyl-2,2-dimethyl-1,3-dioxolane (R)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane 1,3-Dioxolane, 2,2-dimethyl-4-(phenylmethoxy)methyl- L-alpha,beta-isopropylidene glycerol gamma-benzyl ether 1,3-Dioxolane, 2,2-dimethyl-4-(phenylmethoxy)methyl-, (4R)- 1-Benzyl-2,3-isopropylidene-sn-glycerol, L-α,β-Isopropylideneglycerol-γ-benzyl ether
CAS	14347-83-2

1-Benzyl-2,3-isopropylidene-sn-glycerol - Physico-chemical Properties

Molecular Formula	C13H18O3
Molar Mass	222.28
Boling Point	79-80°C0.05mm Hg
Flash Point	110 °C
Appearance	clear liquid
Color	Colorless to Almost colorless
Storage Condition	2-8°C
Refractive Index	n20/D 1.496
MDL	MFCD00066533

1-Benzyl-2,3-isopropylidene-sn-glycerol - Risk and Safety

Safety Description	S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10-23

1-Benzyl-2,3-isopropylidene-sn-glycerol - Introduction

(R)-4-bebzyloxymethyl-2,2-dimethyl-1,3-dioxolane is an organic compound with the chemical formula C11H18O3. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Density: 1.015g/cm³
-Melting point:-60°C
-Boiling point: 200-202°C
-Refractive Index: 1.446

Use:
- (R)-4-bebzyxymethyl-2, 2-dimethyl-1,3-dioxolane is a chiral solvent commonly used in organic synthesis reactions, especially in chiral drug synthesis.
-It can also be used as a protecting group in organic synthesis.

Preparation Method:
(R)-4-bebzyloxymethyl-2,2-dimethyl-1,3-dioxolane can be synthesized by the following steps:
1. Reaction of (R)-4-hydroxy-2, 2-dimethyl-1, 3-dioxopentane with benzyl alcohol to produce (R)-4-benzyloxymethyl-2, 2-dimethyl-1, 3-dioxopentanol.
2. (R)-4-benzyloxymethyl-2, 2-dimethyl-1, 3-dioxopentanol is subjected to dehydration reaction to obtain (R)-4-bebzyloxymethyl-2,2-dimethyl-1,3-dioxolane.

Safety Information:
- (R)-4-bebzyxymethyl-2, 2-dimethyl-1,3-dioxolane has high safety, but it is still necessary to follow appropriate laboratory procedures.
-It may be irritating to the eyes, skin and respiratory tract, so be careful to wear appropriate protective equipment such as gloves, safety glasses and masks during operation.
-Avoid contact with strong oxidants, avoid severe impact and friction.
-Use, storage and disposal in accordance with local regulations. In case of accidental exposure or inhalation, seek medical attention immediately.

Last Update：2024-04-09 20:49:11